Lipoprotein subfractions in patients with depression: The lipoprint system
Tarkan Yazıcı 1, İlkay Bahçeci 2, Süheyl Uçucu 3, Bülent Bahçeci 4
1 Department of Medical Biochemistry, Turkish Ministery of Health Sıtkı Koçman University Research and Training Hospital, 2 Department of Medical Microbiology, School of Medicine, Recep Tayyip Erdoğan University, Rize, 3 Department of Medical Biochemistry, Turkish Ministry of Health Mugla Public Health Care Laboratory, Mugla, 4 Department of Psychiatry, School of Medicine, Recep Tayyip Erdoğan University, Rize, Turkey
DOI: 10.4328/ACAM.20815 Received: 2021-08-13 Accepted: 2021-10-19 Published Online: 2022-03-28 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):470-474
Corresponding Author: Tarkan Yazıcı, Department of Medical Biochemistry, Turkish Ministery of Health Sıtkı Koçman University Research and Training Hospital, Mugla, Turkey. E-mail: firstname.lastname@example.org P: +90 532 542 69 88 Corresponding Author ORCID ID: https://orcid.org/0000-0002-7028-7401
Aim: The aim of the study is to investigate the relationship between depression and changes in 25-OH Vitamin D and Lipoprotein serum levels, which have been suggested to be associated with Central Nervous System neurotransmission and certain psychiatric disorders.
Material and Methods: The study included a patient group consists of 40 depressive individuals who have applied to the Psychiatry outpatient clinic of our hospital and have been first diagnosed with depression according to SCID-1 (Structured Clinical Interview for DSM IV Axis I Disorders) criteria and had no psychiatric or systemic disease that could affect the result, as well as a control group of 40 healthy individuals with similar demographic characteristics. In the collected serum samples, 25-OH vitamin D, LDL, HDL, VLDL, total cholesterol, and TG levels were measured enzymatically and spectrophotometrically; Apolipoprotein Al and Bl00 levels were measured nephelometrically, LDL and HDL subfractions were measured using the Lipoprint System, and then the results were evaluated statistically.
Results: Atherogenic LDL 3 and LDL 4 were significantly higher in the patient group (p=0.001 and p=0.0155, respectively). The mean LDL particle diameter (LDL Mean) was significantly lower in the patient group (p=0.0017). There was no significant difference between the patient and control groups in terms of Buoyant LDL, but Small Dense LDL levels were significantly higher in the patient group (p=0.008 and p<0.001, respectively). LDL 1 Subfraction level of the patient group was statistically significantly higher than the control group (p = 0.0046). There was no significant difference in LDL 2 (p=0.356O).
Discussion: According to the results, LDL 3, LDL 4, and Small Dense LDL serum levels of the patients with depression were found to be higher. The fact that Small Dense LDL has a long circulation time in the blood, atherogenic and proinflammatory properties, better penetrability into the arterial intima layer and is considered as a risk factor in the CVD group, suggests that the risk of atherosclerosis, inflammation and CVD may be higher in patients with depression.
Keywords: Lipoprotein, 25-OH Vitamin D, Depression, Atherosclerosis, Small Dense LDL, LDL Subfractions, Buoyant LDL
Post-recovery pulmonary function test and thorax CT correlations in COVID-19 survivors
Adem Melekoglu 1, Mufide A. Ozkarafakili 2, Derya Ozturk 1
1 Department of Emergency Medicine, 2 Department of Pulmonary and Chest Diseases, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey
DOI: 10.4328/ACAM.20913 Received: 2021-10-22 Accepted: 2022-04-06 Published Online: 2022-04-08 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):475-479
Corresponding Author: Derya Ozturk, Department of Emergency Medicine, University of Health Sciences, Sisli Hamidiye Etfal Education and Research Hospital, Halaskargazi Cd., 34371, Sisli, Istanbul, Turkey. E-mail: email@example.com P: +90 505 279 55 05 Corresponding Author ORCID ID: https://orcid.org/0000-0001-7318-0725
Aim: Long-COVID has been described as persistent symptoms involving multiorgan systems in COVID-19 survivors. This single-centred study investigated the correlation between pulmonary function test (PFT) and thorax computed tomography (CT) results in COVID-19 survivors after six months of follow-up period.
Material and Methods: Patients recovered from COVID-19 aged between 18 and 50 years were included in this study and divided into two groups according to PFT results as patients with normal PFT results (PFT normal; n = 74) and with PFT results with restrictive pattern (PFT restrictive; n = 12). The primary aim of this study was to try to predict the prognosis of long-term chronic pulmonary system diseases using pulmonary function test, thorax CT and laboratory findings in the sixth month after recovery.
Results: There were no significant differences between the patients in PFT normal and PFT restrictive groups in terms of symptoms and CT findings at admission. On the other hand, the rate of dyspnoea and exertional dyspnoea was significantly more pronounced in patients in PFT restrictive group, while there were no significant differences between CT findings. Both univariate and multivariate regression analyses showed that percent forced expiratory volume in one second (%FEV1) and percent forced vital capacity (%FVC) results are associated factors in discriminating normal and PFT results with restrictive pattern in COVID-19 survivors.
Discussion: PFTs should be included in follow-up evaluations of COVID-19 patients in order to elucidate the post-COVID-19 pulmonary abnormalities.
Keywords: Computed Tomography, COVID-19, Long-COVID, Pulmonary Function Test
Galanin-like peptide and leptin levels in polycystic ovary syndrome patients: A case-control study
Fehmi Unal 1, Osman Oğuz 2
1 Department of Obstetrics and Gynecology, 2 Department of Biochemistry, Istanbul Training and Research Hospital, Istanbul, Turkey
DOI: 10.4328/ACAM.20988 Received: 2021-12-10 Accepted: 2022-01-19 Published Online: 2022-01-25 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):480-485
Corresponding Author: Fehmi Unal, Department of Obstetrics and Gynecology, Istanbul Training and Research Hospital, Istanbul, Turkey. E-mail: firstname.lastname@example.org P: +90 533 770 43 96 Corresponding Author ORCID ID: https://orcid.org/0000-0002-8182-2051
Aim: In this study, we aimed to evaluate serum galanin-like peptide (GALP) and leptin levels in women diagnosed with polycystic ovary syndrome (PCOS) and to evaluate its relationship with obesity and insulin resistance.
Material and Methods: This study was conducted with 46 PCOS patients and 33 healthy women matched with a body mass index (BMI). Demographic characteristics of the patients [age, body mass index (BMI), number of births, menstrual characteristics, ovarian and endometrium characteristics], cholesterol, HOMA-IR, GALP, Leptin, AMH, FSH, LH, PRL, DHEA-SO4 and Testosterone levels were measured.
Results: A total of 79 individuals, 46 of whom (58.2%), with a mean age of 25.61 ± 7.15 years (14-43), were diagnosed with PCOS, and 33 of whom (41.8%) were in the healthy control group with similar features in terms of BMI, were included in our study. There was no difference between the groups in terms of GALP levels (3.4 vs. 5.5 ng/ml) (p=0.563). Leptin (10.2 vs. 4.5 ng / ml), AMH (7.3 vs. 2.6 ng / ml) and total testosterone (67.1 ± 25.12 vs. 40.1 ± 19.05 ng / dL) levels in the PCOS group were found to be higher than those in the control group (p<0.001).
Discussion: Our study showed that patients with PCOS had higher leptin and AMH levels than women in the healthy control group with similar BMI values, but there was no significant difference found between the two groups in terms of GALP levels.
Keywords: Galanin-Like Peptide, Leptin, Polycystic Ovary Syndrome
Pain beliefs of hemodialysis patients and non-pharmacological methods they use to relieve pain
Safiye Yanmış 1, Mukadder Molllaoğlu 2
1 Department of Internal Medicine Nursing, Faculty of Health Science, Erzincan Binali Yıldırım University, Erzincan, 2 Department of Nursing, Faculty of Health Science, Sivas Cumhuriyet University, Sivas, Turkey
DOI: 10.4328/ACAM.20992 Received: 2021-12-13 Accepted: 2022-03-03 Published Online: 2022-03-13 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):486-491
Corresponding Author: Safiye Yanmış, Department of Internal Medicine Nursing, Faculty of Health Science, Erzincan Binali Yıldırım University, Erzincan, Turkey. E-mail: email@example.com P: +90 446 226 58 61 Corresponding Author ORCID ID: https://orcid.org/0000-0002-9095-4048
Aim: This study was carried out to determine hemodialysis patients’ pain beliefs and nonpharmacological methods used by patients for pain.
Material and Methods: The research was carried out between July-September 2020. The study was conducted with 103 patients who volunteered to participate in the study, who did not have communication and psychological problems, and who had been on hemodialysis treatment for at least 6 months. The data were collected using patient information form, non-pharmacological methods form used by patients for pain, and a Pain Beliefs Scale. The descriptive statistical methods, Student’s t-test, the One-way Anova and Tukey’s Post Hoc were used in the statistical analysis of the study data.
Results: It was determined that 49.5% used pharmacological methods to relieve pain, 39.8% used non-pharmacological methods to relieve pain. Among the non-pharmacological methods used in pain relief, the most used methods are massage (24.2%) and cold application (14.5%), respectively. It was found that patients’ pain beliefs scale the psychological score average was higher than organic score average.
Discussion: In the study, the nonpharmacological methods that patients use most for pain relief were massage and cold application. It was determined that the patients attribute pain to psychological reasons rather than organic ones. To reduce pain in hemodialysis patients, it is important to apply analgesic treatment according to the doctor’s request, to use nonpharmacological methods used in pain relief by providing interdisciplinary communication and to evaluate the results.
Keywords: Hemodialysis, Nursing, Non-Pharmacological Methods, Pain Beliefs, Pain
Socioeconomic characteristics and risk factors for breast cancer: A case-control study in the Souss-Massa region, Morocco
Zakariae Cherrat 1,2, Rachid Razıne 1,2, Bouchra Amaouı3, Youssef Bouchrıtı 4, Ahmed Id Moussa 5, Majdouline Obtel 1,2
1 Department of Public Health, Clinical Research and Epidemiology (LBRCE), Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, 2 Department of Public Health, Laboratory of Social Medicine, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, 3 Department of Radiology, Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir, 4 Geosciences and Environment Team, Faculty of Sciences, Ibn Zohr University, Agadir, 5 ES-SAADA Laboratory for Medical Analysis, Inezgane, Morocco
DOI: 10.4328/ACAM.20993 Received: 2021-12-15 Accepted: 2022-02-04 Published Online: 2022-02-09 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):492-496
Corresponding Author: Zakariae Cherrat, 21, Crown Prince City, Inezgane, Morocco. E-mail: firstname.lastname@example.org P: +66 215 50 65 Corresponding Author ORCID ID: https://orcid.org/0000-0003-1463-0874
Aim: Across the world, breast cancer is the most common type of cancer affecting women. In Morocco, convincing evidence between several risk factors and breast cancer has been established. The objective of this study is to investigate the socio-economic characteristics and risk factors for breast cancer among women at the Souss-Massa Regional Oncology Center (SMROC).
Material and Methods: A case-control study was conducted at the SMROC. Between May 1 to the end of September 2021, 300 women were recruited, including 150 cases and 150 age-matched controls. Information on the socioeconomic profile of cases and controls and risk factors was obtained using a questionnaire administered by two investigators. The database was created in Excel and statistical analysis was performed using Epi-Info software (version 7).
Results : Low socioeconomic level (OR: 6.7292; 95% CI: 4.0488 – 11.1841), BMI (OR 11.4545; 95% CI: 6.1416 – 21.3636), low Daily Physical Activity (OR: 91.8333; 95% CI: 34.9146 – 241.5423), benign breast disease (OR: 10.5455, 95% CI: 4.0290 – 27.6014), age at first menstruation (OR: 7. 8533; 95% CI: 4.6940 – 13.1389), nulliparity (OR: 2.4225; 95% CI: 1.3244 – 4.4310), use of hormonal contraception (OR: 2.1667; 95% CI: 1.1940 – 3.9318), absence of breastfeeding (OR: 2.2190; 95% CI: 1.2575 – 3.9156), were associated with an increased risk of breast cancer.
Discussion: Our study confirms the multi-factoriality of breast cancer. It is essential to further promote early detection and preventive measures, especially among high-risk population. These results must be confirmed by a multicenter study at the national level.
Keywords: Socioeconomic Characteristics, Risk Factors, Breast Cancer, Morocco
Simultaneous and consecutive operation comparison in bilateral hallux valgus surgery
Kadri Yıldız, Mehmet Eşref Encan, Mehmet Şah Sakçı
Department of Orthopaedics and Traumatology, School of Medicine, Kafkas University, Kars, Turkey
DOI: 10.4328/ACAM.20994 Received: 2021-12-14 Accepted: 2022-01-26 Published Online: 2022-02-28 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):497-501
Corresponding Author: Kadri Yıldız, Kafkas Universitesi Tıp Fakültesi Ortopedi ve Travmatoloji ABD, Ana Kampüs, 36000, Kars, Turkey. E-mail: email@example.com P: +90 538 545 05 59 / +90 474 225 21 06 Corresponding Author ORCID ID: https://orcid.org/0000-0002-8164-7687
Aim: This study aims to determine whether simultaneous bilateral hallux valgus surgery is advantageous over consecutive operations.
Material and Methods: Patients who underwent bilateral hallux valgus surgery were separated into groups Group A and B. Group A included patients who underwent simultaneous bilateral hallux valgus surgery, and Group B who received the consecutive hallux valgus surgery using a Modified Chevron osteotomy techniques with mini-incision. Clinical and radiological databases, complications, mean costs of analgesic drugs, the duration time of surgical operations, the length of hospital stay, the cost of implants, the cost of each group, hospital costs for each patient were determined. The mean in FAOS (Foot and Ankle Outcome Score) scores were calculated for both groups postoperatively.
Results: Patients with bilateral hallux valgus (n=175) were chosen among the hallux valgus patients (n=479). Of these, bilaterally operated patients were accessible about 2/3 (n=101). In Group A (n=30), there were 21 females and 9 males, aged 22–58 years ( mean 41.45±15.12). In Group B (n=35), there were 27 females and 8 males, aged 27–61 years ( mean 45.33±12.64). There was no significant difference in demographic characteristics (p≤0.449) and the follow-up time (p<0.05) between the two groups. The mean hospitalization duration was also shorter in Group A (p≤0.001).
Discussion: Our results demonstrated that simultaneous bilateral hallux valgus surgery is statistically cheaper than consecutive bilateral hallux valgus operation. But, FAOS had slightly better courses in the consecutive bilateral hallux valgus operations compared to simultaneous bilateral hallux valgus operations.
Keywords: Hallux Valgus, Bilateral, Simultaneous, Consecutive, Cost-Effectiveness
Evaluation of knowledge and attitudes of pregnant women about infant oral health and their oral hygiene
Aycan Dal Dönertaş 1, Çağdaş Çınar 2
1 Department of Pediatric Dentistry, Faculty of Dentistry, Nigde Omer Halisdemir University, Niğde, 2 Department of Pediatric Dentistry, Faculty of Dentistry, Gazi University, Ankara, Turkey
DOI: 10.4328/ACAM.20997 Received: 2021-12-15 Accepted: 2022-01-18 Published Online: 2022-01-27 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):502-506
Corresponding Author: Aycan Dal Dönertaş, Department of Pediatric Dentistry, Faculty of Dentistry, Nigde Omer Halisdemir University, 51240, Merkez, Niğde, Turkey. E-mail: firstname.lastname@example.org P: +90 537 723 40 89 Corresponding Author ORCID ID: https://orcid.org/0000-0002-5876-4586
Aim: The aim of this study was to investigate the necessary oral hygiene practices and knowledge level of pregnant women both for themselves and their children.
Material and Methods: Five hundred fifty-five pregnant mothers and mothers with children under 12 months who applied to Gazi University Faculty of Medicine, Pediatrics, Obstetrics and Gynecology Clinics, were surveyed. The first part of the questionnaire consisted of the socio-demographic data of the mothers, the second part consisted of oral health questions related to the mother during the pregnancy period, and the third part consisted of oral health questions about the baby. The data obtained from the survey results were analyzed using IBM SPSS Statistics 17.0 (IBM Corporation, Armonk, NY, USA).
Results: 68.8% of the participants stated that auxiliary dental hygiene devices should be used to provide oral hygiene; 68.1% of the participants thought that there was a relationship between periodontal diseases and pregnancy outcomes. 62% of women reported they should go to the dentist for a dental consultation during pregnancy; 44.7% of the participants reported the baby’s teeth should be brushed after the first tooth eruption, and the majority (64.7%) thought they should be brushed 2 times a day.
Discussion: Our findings are in line with previous reports. Income level was significantly associated with increased use of auxiliary dental hygiene devices and the knowledge that pregnancy could lead to gum problems (p<0,001). Educational level was significantly associated with knowledge about the need for dental consultation, the importance of baby’s general and oral health during pregnancy, and also the knowledge about vertical transition. The time and frequency of tooth brushing did not show a statistically significant difference when the number of pregnancies was examined (p>0,05). However, postgraduate mothers had a significantly higher difference (p<0,001).
Keywords: Infant, Knowledge, Oral Health, Pregnancy, Attitudes
The relationship between fear of COVID-19 and affective symptoms of bipolar patients during the COVID-19 pandemic
Emine Nur Çorum 1, Emrullah Dündar 2
1 Department of Occupational Therapy, 2 Department of Psychiatry, Fatih Community Mental Health Center, Haseki Education and Research Hospital, İstanbul, Turkey
DOI: 10.4328/ACAM.20998 Received: 2021-12-15 Accepted: 2022-03-04 Published Online: 2022-03-13 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):507-511
Corresponding Author: Emine Nur Çorum, Fatih Community Mental Health Center, Haseki Education Research Hospital, 34091, Istanbul, Turkey. E-mail: email@example.com P: +90 212 531 51 04 Corresponding Author ORCID ID: https://orcid.org/0000-0002-9661-4423
Aim: This study aims to examine the relationship between fear of COVID-19 and affective symptoms of patients with bipolar disorder in Turkey. Another aim of the study is to reveal whether participants’ fear of COVID-19 changes according to various socio-demographic characteristics.
Material and Methods: In the study, data were collected from 100 people with bipolar disorder using a face-to-face survey method by a set of scales including the Young Mania Rating Scale, the Hamilton Depression Rating Scale and the Fear of COVID-19 Scale. The data collection process was carried out in October 2020 and January 2021.
Results: The results of the study showed that 53% of the participants had a moderate level of fear of COVID-19, and 45% had a low level of fear. According to the results of the regression analysis, fear of COVID-19 explains 23.1% of the total variance in the mania state. In addition, female bipolar disorder patients were found to have a greater fear of COVID-19 than men.
Discussion: As a result of this study, it was revealed that the manic symptoms of bipolar disorder patients reduced the fear of COVID-19. In this process, detailed scans and interventions for this diagnostic group will be important.
Keywords: Bipolar Disorder, Fear of COVID-19, Pandemic, Mental Disorders
Investigation of the effect of COVID-19 on upper extremity trauma
Hasan Atacan Tonak 1, Yener Aydin 2, Mustafa Icen 2, Bahadir Alimoglu 2, Haluk Ozcanli 2
1 Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, 2 Department of Orthopedics and Traumatology, Faculty of Medicine, Akdeniz University, Antalya, Turkey
DOI: 10.4328/ACAM.20999 Received: 2021-12-15 Accepted: 2022-01-18 Published Online: 2022-01-25 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):512-515
Corresponding Author: Hasan Atacan Tonak, Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Akdeniz University, 07058, Campus, Antalya, Turkey. E-mail: firstname.lastname@example.org P: +90 505 278 22 54 Corresponding Author ORCID ID: https://orcid.org/0000-0002-3545-936X
Aim: Our study aims to evaluate the upper extremity trauma that admitted to our hospital from April 11, 2020, to June 1, 2020, the days when the restrictions were applied in Turkey, and to investigate the effect of COVID-19 on upper extremity trauma by comparing with the data of a year ago between the same dates.
Material and Methods: Demographic information, trauma details, and region, and the treatment method of patients with any upper extremity trauma who were over the age of 18 and admitted to the hospital between April 11, 2019, and June 1, 2019 (2019-Before Restrictions) and between April 11, 2020, and June 1, 2020 (2020-Lockdown) were examined retrospectively.
Results: In 2019-Before Restrictions, 218 patients and in the 2020-Lockdown, 163 patients were admitted to the hospital due to upper extremity trauma. The number of hospital admissions with upper extremity trauma during the 2020-Lockdown was 25.22% less than that of those in 2019-Before Restrictions, (p<0.05). While the number of patients admitted to the hospital due to fractures in the upper extremity during 2019-Before Restrictions, was 89 (Open Fracture=32, Closed Fracture=57), this number was observed to decrease to 48 (Open Fracture=11, Closed Fracture=37) in the 2020-Lockdown (p<0.05).
Discussion: It was determined that there was a decrease in upper extremity trauma during 2020-Lockdown compared to the same dates of the previous year. It is possible to state that quarantine practices applied to prevent the spread of COVID-19 affect the decrease in upper extremity trauma.
Keywords: COVID-19, Upper Extremity, Hand, Trauma, Fracture
Cross-cultural adaptation and validation of the arabic version of the brace questionnaire used for the treatment of adolescents with idiopathic scoliosis
Sarah M. Ali, Nadia A. Fayaz, Sara M. Samir
Department of Physical Therapy for Musculoskeletal Disorder and İts Surgery, Faculty of Physical Therapy, Cairo University, Egypt
DOI: 10.4328/ACAM.21001 Received: 2021-12-16 Accepted: 2022-01-26 Published Online: 2022-02-07 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):516-520
Corresponding Author: Sarah M. Ali, Department of Physical Therapy for Musculoskeletal Disorder and Its Surgery, Faculty of Physical Therapy, Cairo University, Cairo, Egypt. E-mail: Sarah.email@example.com P: +20 103 344 26 56 Corresponding Author ORCID ID: https://orcid.org/0000-0002-8138-3028
Aim: Brace questionnaire (BrQ) is widely used in order to evaluate the impact of brace treatment in adolescent scoliosis on the quality of life. However, it had been translated to different languages, it has not been translated or validated for the Arabic language.
Material and Methods: The Brace questionnaire was translated into Arabic language and back-translated, cross-culturally adapted by experts and according to the international guidelines, then was given to 51 adolescent idiopathic scoliosis patients (46 females and 5 males) were undergoing brace treatment to evaluate its reliability and validity. Reliability was assessed using Cronbach’s alpha for internal consistency and intraclass correlation coefficient (ICC) values for test-retest reliability with a 1-week interval between the tests. Concurrent validity had been made using Pearson’s Correlation Coefficient by correlating the brace questionnaire and the scoliosis research society-22 questionnaire.
Results: The Cronbach’s alpha of the Arabic BrQ was 0.918, the intraclass correlation coefficient (ICC) was 0.938, and the Pearson correlation coefficient between the Arabic Brace questionnaire and Scoliosis research society 22 was 0.758 (p < 0.001).
Discussion: The translated BrQ demonstrated a very good correlation between the Arabic brace questionnaire and the scoliosis research society 22, internal consistency values and concurrent validity were comparable to those of prior studies, wearing the brace and keeping it on for a long time has been shown to have negative effects on overall life quality. Treatment of scoliosis with a brace should not be restricted to clinical and radiological aspects, but should also involve therapeutic education regarding the quality of life.
Keywords: Brace Questionnaire, Quality of Life, Adolescent Idiopathic Scoliosis
Association of root canal treatment and tooth extraction: A clinical audit
Hassan Mohammad 1, Haleema Sadiya 2, Wajid Ali Chatha 1, Saad El Shafey 1
1 Department of Anatomy, College of Medicine, 2 Department of Dentistry, Northern Border University, Arar, Kingdom of Saudi Arabia
DOI: 10.4328/ACAM.21004 Received: 2021-12-16 Accepted: 2022-01-19 Published Online: 2022-01-27 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):521-523
Corresponding Author: Hassan Mohammad, Department of Anatomy, College of Medicine, Northern Border University, Arar, Kingdom of Saudi Arabia. E-mail: firstname.lastname@example.org P: +96 653 864 08 14 Corresponding Author ORCID ID: https://orcid.org/0000-0001-5456-0888
Aim: Dental caries is the most prevalent chronic disease in early childhood in most communities worldwide. Several studies have been conducted and documented a high prevalence of early childhood caries (ECC). The present study aimed to determine the association of root canal treatment that may or not lead to tooth extraction.
Material and Methods: A descriptive study was conducted among 156 patients in the Dental clinic of the university health center. Caries experience was measured using the World Health Organization caries criteria. Descriptive statistics and SPSS were used to calculate the qualitative parameters.
Results: The mean age of patients was 27 years. The statistical analysis revealed that dental caries was significantly associated with inadequate oral hygiene. Adequately done root canal treatment may save the tooth from extraction.
Discussion: The high rate of dental caries and tooth extraction recorded in this study strongly emphasized the necessity of community-based preventive programs and professional dental care.
Keywords: Root Canal, Caries, Pulp, RCT, Tooth Extraction
Gastric residual volume management in a neurosurgery intensive care unit: A randomized controlled trial
Burcu Totur Dikmen 1, Meryem Yavuz van Giersbergen 2, Taşkın Yurtseven 3
1 Department of Surgical Nursing, Faculty of Nursing, Near East University, Nicosia, Cyprus,2 Department of Surgical Nursing, Faculty of Nursing, Ege University, İzmir, Turkey, 3 Department of Neurosurgery, Faculty of Medicine, Ege University, İzmir, Turkey
DOI: 10.4328/ACAM.21008 Received: 2021-12-20 Accepted: 2022-01-21 Published Online: 2022-03-08 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):524-529
Corresponding Author: Burcu Totur Dikmen, Department of Surgical Nursing, Faculty of Nursing, Near East University, Near East Boulevard, 99138, Nicosia, TRNC Mersin 10, Turkey. E-mail: email@example.com P: +90 392 223 64 64 Corresponding Author ORCID ID: https://orcid.org/0000-0002-4221-6112
Aim: This randomized controlled trial aimed to analyze the impact of discarding or returning the aspirated gastric residual volume (GRV) on biochemical values in adult patients.
Material and Methods: The sample of the study consisted of three groups who have just begun to be fed enterally via a nasogastric tube. The first, second and control groups each included 30 patients. In the first group, GRV aspirated from the patients was given back to the patients, while in the second group, GRV was discarded. The third group was the control group, GRV was not checked.
Results: Between the three groups there was no statistically significant difference in GRV, the blood levels of aspartate amino transferase (AST), alanine amino transferase (ALT), C-reactive protein (CRP), prealbumin, transferrin, cholesterol, hemoglobin, hematocrit, urea, creatinine, electrolyte and glucose (p>.05), but the levels of triglycerides and phosphorus varied significantly among the three groups (p<.05).
Discussion: There is no difference was found between the groups of returning, discarding the aspirated GRV and control group, in terms of patients’ AST, ALT, CRP, hemoglobin, hematocrit, transferrin, prealbumin, total cholesterol, urea, creatinine, sodium, potassium, chlorine, calcium, magnesium and glucose values, but differences were found between the groups in triglyceride and phosphorus values.
Keywords: Gastric Residual Volume, Intensive Care Units, Nursing, Neurosurgery
Is it possible to evaluate the hypernatremia with ultrasonographic vena cava parameters?
Dilek Atik 1, Basar Cander 3, Emre Gokcen 2, Ramazan Unal 3, Cesareddin Dikmetas 3,Nuray Kılıc 2
1 Department of Emergency Medicine, Karamanoglu Mehmetbey University, Karaman, 2 Department of Emergency Medicine, Yozgat Bozok University, Yozgat, 3 Department of Emergency Medicine, Health Sciences University, Kanuni Sultan Suleyman Research and Training Hospital, Istanbul, Turkey
DOI: 10.4328/ACAM.21012 Received: 2021-12-20 Accepted: 2022-01-21 Published Online: 2022-01-25 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):530-534
Corresponding Author: Dilek Atik, Acil Tıp Ana Bilim Dali, Karamanoglu Mehmetbey Universitesi, İbrahim Öktem Cd., 70100, Karaman, Turkey. E-mail: firstname.lastname@example.org P: +90 354 212 44 42 F: +90 354 217 10 72 Corresponding Author ORCID ID: https://orcid.org/0000-0002-3270-8711
Aim: In this study, we aimed to evaluate the relationship of inferior vena cava (IVC) respiratory variation with hypernatremia due to fluid response, and to evaluate its applicability in determining SNa levels in these patients.
Material and Methods: Geriatric patients with dehydration and hypernatremia were included in the study. In the inferior vena cava (IVC) measurement, the diameter of the IVC was measured for each patient by different emergency physicians using experienced and trained sonography. This prospective, cross-sectional and observational study was conducted as a double centre study from January to July 2020.
Results: The evaluation was performed on 103 patients. Of the 103 dehydrated patients included in the study, 78 (75.7%) had mild hypernatremia (Serum Sodium (SNa)145-154 mEq/L), and 25 (24.3%) patients had severe hypernatremia (SNa>155 mEq/L). When patients with hypernatremia were divided into two groups as mild and severe, the diagnostic efficiency of the VCI diameter, IVCCI parameters and the ROC curve and AUC, cut-off, sensitivity and specificity were discriminately analyzed to guide the patient’s condition in the patient follow-up. For the VCI diameter parameter, the AUC, cut-off, sensitivity and specificity were 0.893 %, 14.7%, 65.2% and 95.2%, respectively. IVCCI AUC, cut-off, sensitivity, and specificity were 0.756, 56.19, 73.9% and 70%, respectively.
Discussion: IVC and IVCCI can be used to identify patients with dehydration-induced hypernatremia and determine disease severity, and moreover, they can be used as a useful tool in the assessment of adequate fluid volume replacement in the follow-up of these patients.
Keywords: Inferior Vena Cava (IVC), IVCCI; Dehydration, Geriatric Patients, Ultrasonography, Hypernatremia
Increase in cesarean delivery rates is the biggest obstacle to the reduction of feto-maternal morbidity
Department of Obstetrics and Gynecology, Istanbul IVF-Center, Istanbul, Turkey
DOI: 10.4328/ACAM.21015 Received: 2021-12-22 Accepted: 2022-02-04 Published Online: 2022-02-05 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):535-538
Corresponding Author: Ramazan Ozyurt, Istanbul IVF-Center, Istanbul, Turkey. E-mail: email@example.com P: +90 532 748 34 90 Corresponding Author ORCID ID: https://orcid.org/0000-0001-6822-2222
Aim: Cesarean delivery, whose incidence is already high, has started to increase due to the increase in both labor induction and multiple pregnancy rates due to ART. The cesarean section rate to reduce maternal and fetal morbidity should be 10% or less. This study was planned to compare cesarean and vaginal delivery rates, indications, fetal and maternal morbidity and mortality rates performed in Istanbul Training and Research Hospital over a ten-year period.
Material and Methods: During the ten-year period between January 2000 and January 2009, 17150 patients who gave birth were included in the study. Demographic data of the patients were obtained retrospectively from their files. Maternal age, gravida, parity, length of hospital stay and cesarean section indications were recorded. Those who had one or more previous cesarean sections and those who had previous cesarean section due to myomectomy constituted the secondary cesarean section group. Those who had a cesarean section for the first time constituted the primary cesarean section group. Frequency of normal and cesarean delivery rates, indications for cesarean section, early and late maternal and fetal morbidity and mortality rates were compared.
Results: The total number of patients participating in the study, including normal vaginal delivery and cesarean section, was determined as 17150. While 9310 of them gave birth by cesarean section, 7840 cases delivered vaginally. While the number of patients with previous and repeated cesarean section was 3180, the number of patients with first cesarean section was 6130. Previous and repeated cesarean sections were recorded as the most common cesarean indication (48%). The second most common cesarean indication is fetal distress (18.4%). The third most common indication for cesarean section is cephalo-pelvic incompatibility (11.2%), which was found in 67 cases. The fourth most common cesarean indication is presentation-position anomaly, which was detected in 53 cases (8.8%). When compared with the primary cesarean section group, the rates of hemorrhage, urinary infection, fever, wound dehiscence and re-operation were found to be significantly higher in the secondary cesarean section group. When compared with the secondary cesarean section group, fetal birth weight was found to be significantly higher in the primary cesarean section group. Fetal length, head circumference, 1st and 5th minute APGAR scores were found to be similar in both groups.
Discussion: Despite efforts by healthcare providers and governments to promote normal vaginal delivery, both cesarean section and feto-maternal morbidity continue to increase.
Keywords: Cesarean Section, Vaginal Delivery, Fetal Morbidity, Maternal Morbidity
Evaluation of sexual functions between suffers of chronic spontaneous urticaria and psoriasis
Mehmet Yunus Meydan 1, Ayşe Nilhan Atsü 2, Nazlı Caf 1, Zafer Türkoğlu 1
1 Department of Dermatology, Başakşehir Çam and Sakura City Hospital, 2 Faculty of Health Sciences, İstanbul Kent University, Istanbul, Turkey
DOI: 10.4328/ACAM.21016 Received: 2021-12-22 Accepted: 2022-01-24 Published Online: 2022-02-09 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):539-543
Corresponding Author: Nazlı Caf, Department of Dermatology. Olimpiyat Bulvarı Yolu, Başakşehir Çam and Sakura City Hospital, Başakşehir, Istanbul, Turkey. E-mail: firstname.lastname@example.org P: +90 212 909 60 00 Corresponding Author ORCID ID: https://orcid.org/0000-0001-9364-9236
Aim: Chronic dermatological diseases may have psychosocial effects such as sexual dysfunction. In this study, we aimed to evaluate the effects of chronic spontaneous urticaria (CSU) and psoriasis on sexual functions in comparison with healthy individuals.
Material and Method: Patients having psoriasis and CSU were enrolled. Healthy controls were obtained from volunteered patients applied for dermo-cosmetic product consultation. Thirty male and 30 female participants were included in every group. Beck Depression and Anxiety scales were administered to all participants. Female Sexual Function Index (FSFI) scale was applied to female participants and International Index of Erectile Function (IIEF) scale to males. Dermatology Life Quality Index (DLQI), Urticaria Activity Score of 7 (UAS7), and Urticaria Control Test (UCT) were applied to the patients belonging to CSU group. Data were analyzed with the IBM SPSS (Statistical Package for the Social Sciences) 22.0 program.
Results: Beck Anxiety scores did not differ between the groups (p>0.005). FSFI did not differ significantly between psoriasis and CSU groups (p>0.005), but it was significantly higher in healthy controls. IIEF did not differ between psoriasis and CSU groups. DLQI and UAS7 were negatively correlated with IIEF and FSFI sub-parameters (p<0.01).
Discussion: Our study is unique in evaluating sexual functions in CSU, psoriasis patients, and healthy individuals; therefore, adds to the literature. The psychosocial effects of chronic dermatoses such as CSU and psoriasis are not limited to depression, anxiety, and sleep disorders. Sexual functions should also be assessed and included in the treatment plan.
Keywords: Psoriasis, Chronic Urticaria, Sexual Dysfunction
Evaluation of corneal endothelial morphology in type 2 diabetes mellitus with specular microscopy
Murat Serkan Songur 1, Murat Akansel 1, Seray Aslan Bayhan 1, Tekin Yıldırım 2, Hasan Ali Bayhan 1
1 Deparment of Ophthalmology, 2 Deparment of Internal Medicine, Faculty of Medicine, Yozgat Bozok University, Yozgat, Turkey
DOI: 10.4328/ACAM.21019 Received: 2021-12-23 Accepted: 2022-01-24 Published Online: 2022-01-25 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):544-547
Corresponding Author: Murat Serkan Songur, Deparment of Ophthalmology, Faculty of Medicine, Yozgat Bozok University, Çapanoğlu Mahellesi, Cemil Çiçek Caddesi, Yozgat, 66100, Turkey.
E-mail: email@example.com P: +90 505 798 85 28 F: +90 354 217 10 72 Corresponding Author ORCID ID: https://orcid.org/0000-0001-6234-3680
Aim: In this study, we aimed to evaluate the corneal endothelium using a specular microscopy in patients with type 2 diabetes mellitus (DM).
Material and Methods: The right eyes of 30 DM patients without any ocular findings, 30 DM patients with non-proliferative diabetic retinopathy (NPDR), and 30 DM patients with proliferative diabetic retinopathy (PDR) were evaluated in the study. Cell density (cells/mm2), corneal thickness (µ), hexagonal cell ratio (%), and coefficient of variation (cell area standard deviation/mean cell area, µm2) of the corneal endothelium of these patients were assessed with a specular microscope.
Results: There was no significant difference between the groups in terms of corneal thickness. While there was no significant difference between the control group and the group with NPDR in terms of endothelial cell density, hexagonality and coefficient of variation, a significant difference was found between the PDR group and both the control and NPDR groups.
Discussion: Since we found that disease progression leads to deterioration in corneal endothelial morphology in type 2 DM patients, we believe that it is important to try to prevent disease progression by controlling the blood glucose levels and using specular microscopy during follow-up and treatment in these patients.
Keywords: Type 2 Diabetes Mellitus, Specular Microscopy, Corneal Endothelium, Hexagonality, Coefficient of Variation
Scientometric analysis of methanol intoxication literature: Global publication output between 1980 and 2019
Umut Payza 1, Engin Şenel 2, Fatih Esad Topal 1, Zeynep Karakaya 1, Mehmet Göktuğ Efgan 1
1 Department of Emergency Medicine, Katip Celebi University, Ataturk Research and Training Hospital, İzmir, 2 Department of Dermatology and Venereology, Hitit University, Corum, Turkey
DOI: 10.4328/ACAM.21020 Received: 2021-12-23 Accepted: 2022-02-07 Published Online: 2022-02-08 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):548-553
Corresponding Author: Mehmet Göktuğ Efgan, Department of Emergency Medicine, Katip Celebi University, Ataturk Research and Training Hospital, İzmir, Turkey. E-mail: firstname.lastname@example.org P: +90 546 674 19 70 Corresponding Author ORCID ID: https://orcid.org/0000-0002-0794-1239
Aim: Scientometrics refers to the analysis of scientific literature related to a certain field. Even though the number of publications on methyl alcohol poisoning has recently increased, there has been no bibliometric or scientometric analysis conducted to date. In 2020 in particular, cases of methyl alcohol poisoning have increased due to the COVID-19 pandemic, which is expected to draw greater attention to this field.
Material and Methods: All data used in this study were collected from four databases accessed via the Web of Science. All studies published between 1980 and 2019 identified by searching for the keywords “methanol” and “poisoning” were included in the study. The relationship between the number of publications and productivity and characteristics of countries was analyzed with Spearman’s correlation test, while GunnMap and VOSviewer were used to create infographics and infomaps. This study was conducted in accordance with the Declaration of Helsinki
Results: A total of 744 articles, most of which were original (79.70%), were identified from the four databases accessed via the Web of Science. An analysis of the number of publications by country ranked the United States in the first place, with 174 articles (23.387 %), while the Czech Republic was found to have the most productive researchers. The most popular area was toxicology (20.565%), and Charles University was the most productive institution. It was found that the number of publications and citations did not increase over the years
Discussion: The developed countries dominated the literature on methyl alcohol poisoning. It was further observed that articles on methyl alcohol abuse started to appear in 2020 in developing countries, which can be attributed to the COVID-19 pandemic, and the mistaken belief that it has anti-viral properties. Since the diagnosis and treatment of methyl alcohol poisoning are gaining significance, we recommend that researchers be encouraged to make further studies in this area.
Keywords: Bibliometrics, Citation Analysis, Methanol, Intoxication, Scientometrics
Surgical treatment of displaced radial neck fractures in children with metaizeau technique: Late-term results
Hakan Koray Tosyalı 1, Sertan Hancıoğlu 1, Hüseyin Kaya 2, Güvenir Okçu 1, Kemal Aktuğlu 2
1 Department of Orthopedic and Traumatology, Faculty of Medicine, Celal Bayar University, Manisa, 2 Department of Emergency Medicine, Faculty of Medicine, Ege University, Izmir, Turkey
DOI: 10.4328/ACAM.21021 Received: 2021-12-23 Accepted: 2022-01-24 Published Online: 2022-02-02 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):554-557
Corresponding Author: Hakan Koray Tosyalı, Department of Orthopedic and Traumatology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey. E-mail: email@example.com / firstname.lastname@example.org P: +90 532 450 78 55 Corresponding Author ORCID ID: https://orcid.org/0000-0002-1624-1912
Aim: In this study, we aimed to analyze the functional and radiological outcomes of displaced radial neck fractures in children treated with the Metaizeau technique .
Material and Methods: This was a retrospective study, and data were collected prospectively. Thirty-eight patients with grade III and grade IV radial neck fractures according to the classification of Judet et al were managed surgically by Metaizeau technique. All patients were surgically treated with percutaneous k-wire leverage reduction and retrograde transphyseal k-wire fixation. The functional results were evaluated using the Metaizeau functional scoring system. Clinical evaluation and results were performed using the Mayo elbow performance score (MEPS), ROM of the elbow (flexion, extension) and forearm (supination, pronation) was measured with a goniometer. Complications were also evaluated.
Results: The average follow-up time was 64.9 months (28 -120 months), there were no patients with nonunion, avascular necrosis, infection, posterior interosseous nerve (PIN) injury, heterotopic ossification or radioulnar synostosis. There were 31 (88.5 %) excellent or good results and 4 (11.5 %) fair results according to the Metaizeau classification. The final X-rays showed fracture healing in all patients. No patient developed complications.
Discussion: Intramedullary pinning, as described by Métaizeau, is a reliable and reproducible surgical method to treat radial neck fractures in children, which provides excellent or good results and has a low risk of complications. Level of evidence IV (case series and systematic review of level IV studies).
Keywords: Radial Neck Fracture, Pediatric Elbow Injury, Pediatric Trauma, Metaizeau Technique
Optical coherence tomography findings in patients with beta thalassemia major
Cenk Zeki Fikret 1, Filiz Yildirim 2, Nil Irem Ucgun 3, Ozlem Evren Kemer 3
1 Department of Ophthalmology, Ankara City Hospital, 2 Clinic of Internal Medicine, Polatlı Duatepe Goverment Hospital, 3 Department of Ophthalmology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey
DOI: 10.4328/ACAM.21028 Received: 2021-12-27 Accepted: 2022-02-10 Published Online: 2022-02-28 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):558-562
Corresponding Author: Filiz Yildirim, Clinic of Internal Medicine, Polatlı Duatepe Goverment Hospital, Polatlı, 06900, Ankara, Turkey. E-mail: email@example.com P: +90 544 411 22 89 F: +90 312 243 10 12 Corresponding Author ORCID ID: https://orcid.org/0000-0002-6151-2697
Aim: In this study, we aimed to evaluate macular ganglion cell layer + (GCL+), retinal nerve fiber layer (RNFL), choroidal thickness and Hood report pathologies with swept-source optical coherence tomography (SS-OCT) in beta-thalassemia major patients.
Material and Methods: Twenty-four eyes of 24 multi and regular blood transfused beta-thalassemia major patients on chelation therapy (thalassemic group) and age- and sex- matched 25 eyes of 25 healthy individuals (control group) were included in the study. Macular GCL+, peripapillary total RNFL, and subfoveal choroidal thickness measurements were obtained in patients with beta-thalassemia major. SS-OCT images were collected from Topcon DRI OCT Triton SS-OCT (Topcon, Tokyo, Japan). Glaucoma and Hood reports were derived from Rescan 3D(H)+Line(H) mode. Choroidal thickness was measured from macular radial mode.
Results: In the thalassemic group, the mean values were 74.00±7.18 µm for macular GCL+ thickness; 122.75±11.37 µm for total RNFL; 423.08±32.64 µm for choroidal thickness; 255.50±18.48 µm for macular thickness. In the control group, the mean values were 61.84±8.04 µm for macular GCL+ thickness; 108.88±4.98 µm for total RNFL; 323.00±26.94 µm for choroidal thickness; 249.12±17.07 µm for macular thickness. GCL+, total RNFL and choroidal thickness in the thalassemic group were significantly thicker than in the control group (p<0.001). There was no difference between the two groups in terms of macular thickness (p>0.05). There was a positive correlation between choroidal thickness and ferritin levels in the thalassemic group (r=0.630, p<0.01).
Discussion: RNFL and GCL+ values are important, but we must also review the Glaucoma and Hood reports on patients with beta thalassemia major to detect ocular involvement. Choroidal thickness measurements should also be performed in these patients. The positive correlation between ferritin levels and choroidal thickness in thalassemic patients suggests that ferritin levels may be effective in ocular findings.
Keywords: Thalassemia Major, GCL, RNFL, Choroidal Thickness, OCT
Efficacy of a home exercise program on balance, kinesiophobia, pain and quality of life in post-COVID-19 patients
Aysun Özlü, Fatıma Yaman, Merve Akdeniz Leblebicier, Dilan Bulut Özkaya
Department of Physical Medicine and Rehabilitation, Kutahya Health Science University, Kutahya, Turkey
DOI: 10.4328/ACAM.21033 Received: 2021-12-30 Accepted: 2022-02-02 Published Online: Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):563-567
Corresponding Author: Aysun Özlü, Kütahya Sağlık Bilimleri Üniversitesi, Kütahya, Türkiye. E-mail: firstname.lastname@example.org P: +90 505 398 94 44 Corresponding Author ORCID ID: https://orcid.org/0000-0002-1912-6039
Aim: In this study, we aimed to determine the effects of a home exercise program on patients who treated for COVID-19 in the pandemic ward.
Material and Methods: In this randomized, clinical, single-blinded, controlled study, 82 patients who were discharged after completing their COVID-19 treatment were included in the study, and demographic data were recorded by dividing them into two groups as experimental (n=42) and control (n=40). Joint range of motion (ROM) and balance exercises were recommended for the experimental group as a home exercise program, while the control group did not receive any intervention. The home exercise program was implemented 5 days a week for 4 weeks. All the patients were evaluated in terms of quality of life (Nottingham Health Profile (NHP)), kinesiophobia (Tampa Scale of Kinesiophobia), balance (Berg Balance Scale), pain (Visual Analog Scale) before and after the intervention.
Results: In both groups, a statistically significant difference was observed in the quality of life, balance and pain levels after the intervention (p<0.05). After the intervention, there was a statistically significant improvement in kinesiophobia in the experimental group (p<0.05), no statistically significant difference was found in kinesiophobia in the control group (p<0.05). In the comparison between the groups after intervention, a statistically significant difference was observed in terms of quality of life (NHP part 2), kinesiophobia, balance, with the results being in favor of the experimental group.
Discussion: ROM and balance exercises for post-COVID-19 patients at the time of discharge are effective in improving quality of life, balance and kinesiophobia, but their effects on pain remain unclear.
Keywords: Home Exercise Program, Balance, Kinesiophobia, COVID-19
COVID-19 in pediatric patients: Data from a training and research hospital
Emine Yurdakul Erturk 1, Ozden Aksu Sayman 1, Onur Yalcin 2
1 Department of Pediatrics, 2 Department of Pediatric Surgery, Ordu University, Training and Research Hospital, Ordu, Turkey
DOI: 10.4328/ACAM.21038 Received: 2022-01-01 Accepted: 2022-02-03 Published Online: 2022-02-10 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):568-572
Corresponding Author: Emine Yurdakul Erturk, Department of Pediatrics, Faculty of Medicine, Ordu University, 52200, Altınordu, Ordu, Turkey. E-mail: email@example.com P: +90 505 389 27 71 F: +90 452 226 52 28 Corresponding Author ORCID ID: https://orcid.org/0000-0001-5366-647X
Aim: Coronavirus Disease-19 (COVID-19), caused by severe acute syndrome coronavirus 2 (SARS-CoV-2), has become a worldwide emergency. It is known that the course of the disease in pediatric COVID-19 is milder, with a better prognosis and lower rate of deaths. However, epidemiological and clinical data on children with COVID-19 are still scarce. The aim of this study is to describe the demographic, clinical and laboratory findings of children with COVID-19.
Material and Methods: Medical records of patients aged under 18 years who had polymerase chain reaction (PCR) test for SARS-CoV-2 between March 15, 2020 and September 14, 2020 were examined retrospectively.
Results: Of the 108 children infected with SARS-CoV-2, 52 (48.1%) were female, 56 (51.9%) were male, and the median age was 9 years (0-17 years). The most common presentation symptoms included fever (54.6%), fatigue or myalgia (32.4%), and cough (30.5%). Of all patients, 63.9% (n=53) had lymphopenia. Seventy (67.3%) cases with COVID-19 had a contact history. The median time from symptom onset to diagnosis was 1 (0-8) day. Posteroanterior chest X-ray was ordered in 80.5% (n=87) of the SARS-CoV-2 PCR positive patients, and only 5.7% (n=5) had findings in favor of infiltration. Chest computed tomography was ordered in four (3.7%) children, and one (25%) of them had findings consistent with COVID-19. Eight patients were hospitalized, one of whom was followed-up in the intensive care unit, and no patients died.
Discussion: A better understanding of the clinical and laboratory characteristics of COVID-19 infection in children is very important in developing influential strategies to manage the disease.
Keywords: Children, COVID-19, SARS-CoV-2
Relationship between inflammation related index and coronary artery disease in low-to-moderate risk patients with stable chest pain
Department of Cardiology, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey
DOI: 10.4328/ACAM.21039 Received: 2022-01-02 Accepted: 2022-02-08 Published Online: 2022-02-09 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):573-578
Corresponding Author: Ferıt Boyuk, Department of Cardiology, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey. E-mail: firstname.lastname@example.org P: +90 539 287 78 60 Corresponding Author ORCID ID: https://orcid.org/0000-0003-2313-1495
Aim: Coronary artery disease is the leading cause of mortality and morbidity worldwide. Recently, inflammatory markers found and measured in the complete blood count have been used as precursors in many clinical situations. In this study, we aimed to investigate the relationship between inflammatory-related hemogram parameters and coronary artery disease in low-to-moderate risk patients with stable chest pain.
Material and Methods: A total of 101 patients who underwent CT coronary angiography between 2018 and 2020 were included in the study. Patients were classified as those with normal coronaries, coronary plaques, and severe coronary stenosis. Severe coronary stenosis was represented as at least one of >50% stenotic coronary vessels and the relationship between hemogram parameters and coronary artery disease was retrospectively investigated.
Results: There was no significant difference between healthy, coronary plaque, and severe stenosis groups in terms of RDW, Platelet to Lymphocyte Ratio (PLR), and Monocyte to High Dens Lipoprotein Ratio (MHR). The only significant difference among the groups was for neutrophil/lymphocyte ratio (NLR)(p=0.015). NLR was significantly higher in the severe coronary stenosis (44.46±8.65) compared to the healthy (1.76±0.58) and coronary plaque (1.77±0.64) (p=0.005 and 0.012; respectively) groups. No difference was found between the healthy and coronary plaques in terms of NLR (p=0.989).
Discussion: Although we did not identify a parameter that could be defined as a diagnostic value among these indexes, NLR appears to be stronger than others in the low-to-moderate risk group.
Keywords: Chest Pain, Angiography, Platelet, Lymphocyte, Neutrophil, Monocyte
Assessment of post-COVID-19 clinical manifestations after recovery in healthcare professionals
Anam Arshad 1, Iram Arshad 1, Muhammad Humayun 1, Asmara Syed 2, Ekramy Elmorsy 2, Syed Sajid Hussain Shah 2
1 Department of Biochemistry, Central Park Medical College, Lahore, Pakistan, 2 Department of Pathology, Faculty of Medicine, Northern Border University, Arar, Kingdom of Saudi Arabia
DOI: 10.4328/ACAM.21042 Received: 2022-01-05 Accepted: 2022-02-09 Published Online: 2022-02-16 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):579-582
Corresponding Author: Anam Arshad, Department of Biochemistry, Central Park Medical College, Lahore, Pakistan.
E-mail: email@example.com P: +92 320 000 87 67 Corresponding Author ORCID ID: https://orcid.org/0000-0003-3879-4291
Aim: In this study, we aimed to assess the COVID -19 clinical manifestations after recovery from illness among healthcare professionals.
Material and Methods: After ethical approval, a structured questionnaire has been distributed among healthcare professionals who were willing to participate in the study. The questionnaire contained forty questions, which were divided into four sections.
Results: A total of 126 participants completely filled the questionnaire, including 65 (51.6%) females and 61(48.4%) males. Fatigability is the most common (38.1%) post-COVID clinical manifestation in healthcare professionals. Other common post- COVID clinical manifestations are numbness in the face/ arms/legs (34.2%), cough (23%), muscle pain (20.6%) and anxiety/depression (20.6%) in order of frequency.
Discussion: The presence of fatigue, anxiety, cough and hair fall was observed in women healthcare workers up to 2 months even after recovery from mild to moderate disease.
Keywords: COVID-19, Clinical Manifestations, Health Professionals
Evaluation of the oxidant/antioxidant status in patients with brucellosis treated with a combination of two types of antibiotics
Department of Biochemistry, Health Science Faculty, Cankiri Karatekin University, Cankırı, Turkey
DOI: 10.4328/ACAM.21045 Received: 2022-01-14 Accepted: 2022-04-12 Published Online: 2022-04-13 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):583-587
Corresponding Author: Emrah Caylak, Saglık Bilimleri Fakultesi, Karatekin University, 18200, Cankiri, Turkey. E-mail: firstname.lastname@example.org P: +90 544 613 49 99 Corresponding Author ORCID ID: https://orcid.org/0000-0003-0408-9690
Aim: This study aimed to evaluate the oxidant/antioxidant status of patients treated for brucellosis and to determine the effects of a combination of antimicrobial agents (doxycycline, streptomycin and rifampicin) that could be used in the treatment of brucellosis.
Material and Methods: Sixty (60) acute patients with brucellosis and thirty (30) healthy volunteers were enrolled in the study. Doxycycline-streptomycin (DOX-STR) and doxycycline-rifampicin (DOX-RIF) were used in the treatment of brucellosis. MDA levels, total oxidant status (TOS), and superoxide dismutase, catalase levels and total antioxidant capacity (TAC) were determined in patients treated with brucellosis. Also, TOS/TAC index (OSI) was calculated.
Results: Before therapy, MDA, TOS, SOD, catalase levels and OSI value were significantly higher, and TAC was significantly lower in brucella patients compared with healthy subjects (p < 0.001). After therapy, MDA, TOS, SOD, catalase levels, and OSI value significantly decreased, and plasma TAC levels significantly increased compared to the pre-treatment group, especially in the DOX-STR regimen (p < 0.001).
Discussion: Over-production of oxidants and depletion of TAC in patients with brucellosis are associated with inflammatory nature of brucellosis. Measurement of oxidant/antioxidant status may be useful for monitoring patients who are recovering, and the treatment of patients with antibiotic combination, especially (DOX-STR) will ameliorate their antioxidant system.
Keywords: Brucellosis, Total Oxidant Status (TOS), Total Antioxidant Capacity (TAC), Oxidative Stress Index (OSI), Treatment; Antibiotic Combination
Comparison of maternal and perinatal outcomes of pregnancies with frozen and fresh embryo transfers at term pregnancy
Jule Eriç Horasanlı, Hasan Energin, Enes Ferlibaş
Department of Gynecology and Obstetrics, Meram Faculty of Medicine, Necmettin Erbakan Üniversity, Konya, Turkey
DOI: 10.4328/ACAM.21046 Received: 2022-01-08 Accepted: 2022-02-11 Published Online: 2022-02-22 Printed: 2022-05-01 Ann Clin Anal Med 2022;13(5):588-591
Corresponding Author: Jule Eriç Horasanlı, Department of Gynecology and Obstetrics, Meram Faculty of Medicine, Necmettin Erbakan Üniversity, Konya, Turkey. E-mail: email@example.com P: +90 555 479 33 94 Corresponding Author ORCID ID: https://orcid.org/0000-0002-8738-7126
Aim : In our study, we aimed to compare maternal and perinatal outcomes of frozen and fresh embryo transfers, induced by single or double embryo transfer with in vitro fertilization (IVF) at term pregnancy.
Material and Methods: After obtaining ethics, our study was performed retrospectively assessing pregnancies in women between the ages of 18 and 40 induced with single or double embryo transfer with IVF between the years 2010 and 2020. Maternal outcomes such as oligohydramnios, polyhydramnios, preeclampsia, placenta previa, placenta accreta syndrome (PAS), and hysterectomy were examined in all groups. Perinatal outcomes including birth weight, time of delivery, small for gestational age (SGA), large for gestational age (LGA), appropriate for gestational age (AGA), preterm labor, Apgar score of infant at five minutes, and intensive care requirement were also investigated.
Results: No difference was observed in terms of oocyte number collected, neonatal intensive care requirement, Apgar scores, postpartum hysterectomy, and blood transfusions. There was no difference between the groups in birth weight, preterm labor, and delivery time. There was no significant difference between the groups in SGA, LGA, and AGA. Polyhydramnios and oligohydramnios were significantly higher in the fresh transfer group (p = 0.006 and p = 0.006, respectively). Among perinatal parameters, the frequency of placenta previa was significantly higher in the frozen transfer group (p = 0.001). The frequency of placenta accreta and preeclampsia was not significantly different.
Discussion: Placenta previa was higher in the frozen transfer group, suggesting frozen embryo transfer increases the risk of placenta previa. Oligohydramnios and polyhydramnios were higher in the fresh transfer group.
Keywords: IVF, Frozen Transfers, Fresh Transfers, Outcomes, Term Pregnancy