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Guidelines

Please submit your articles in accordance with these formatting rules and guidelines, which have been prepared to ensure stylistic consistency for our journal.

Manuscript Language

Articles and abstracts should be submitted in English. They should be evaluated by a language expert, and this should be indicated on the Presentation to the Editor page.

If the language expert is not one of the authors, their name must be included in the Acknowledgement section of the article.

A Statement That the Manuscript Is Not Published Elsewhere

Each author must declare that the submitted manuscript, either in full or in part, has not been previously published and is not currently under consideration for publication in either printed or digital form. This rule applies to all content, except abstracts of 400 words or fewer, and includes presentations, books, articles, and other forms of information dissemination, whether in print or electronic format.

Authors are required to obtain written consent from the original author and copyright holder for any quotations taken from previously published works. This consent should be documented within the manuscript and submitted along with it. If a study has been previously presented at a congress, conference, or as a poster presentation, this must be indicated on the title page, specifying the date, conference name, and location.

Assessment

Please review the journal’s guidelines carefully before submitting your manuscript. Articles that do not comply with the formatting requirements will be returned to the author without further review. Submitted manuscripts will be evaluated by two or more national or international reviewers who are experts in the field and not part of our editorial team. Articles are assessed based on their importance, originality, and scientific validity. After the peer review process, the manuscript will also be reviewed by the editorial board.

If necessary, the editorial board may correct spelling or grammar errors without altering the content. Additionally, the editorial board has the authority to request modifications to the content or format of the article or to ask that the article be shortened. If such changes are required, authors will be informed in writing. Articles will not be published until these revisions are completed. Once the manuscript has been submitted, no additions or deletions to the author list may be made without written consent from all authors.

Acceptance for Publication

If approved by the editorial board, submitted manuscripts will be scheduled for publication.

Handling of Unaccepted Manuscripts

In line with international publication ethics (AMA, ICMJE, COPE, WAME), unaccepted manuscripts and files are not returned and are permanently deleted from the system soon after the editorial decision..

Copyright and License Agreement

The copyright of all published articles remains with the author(s). By submitting the Copyright & License Agreement form, the author(s) grant the Annals of Clinical and Analytical Medicine (ACAM) a non-exclusive license to publish the work under the Creative Commons Attribution–NonCommercial 4.0 International License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/). This license allows others to share, adapt, and distribute the work for non-commercial purposes with proper citation of the original source. Any commercial use of articles, data, tables, figures, or videos published in ACAM requires prior written permission from the publisher, even if derived from the authors’ own work. The corresponding author must upload a Copyright & License Agreement form signed by all authors during the online submission process. No payment or royalty is provided to authors for submitted or published manuscripts. The full responsibility for the scientific content rests with the authors.

Scientific Responsibility Statement

Authors must declare in the Copyright Transfer Form of the accepted article that they are responsible for the scientific content of the article. These areas of responsibility include study design, data collection, analysis and interpretation, writing, preparation and scientific review of the content, and approval of the final version of the article.

Submission Step to the Journal

Manuscript authors are not compensated in any way for their manuscripts. The content of the articles is entirely the responsibility of the author. For any commercial use of material from this open-access journal, permission must be obtained from the Annals of Clinical and Analytical Medicine.

SCIENTIFIC ASSURANCE: ACAM

Annals of Clinical and Analytical Medicine (ACAM) upholds scientific integrity and unwavering adherence to ethical values as its core principles.

Each submission undergoes a rigorous double-blind peer-review process to ensure compliance with the highest academic standards.

This commitment reinforces both the quality of publications and the trust in scientific research, while maintaining alignment with international ethical publishing standards.

Style Guidelines

Authors should adhere to the Uniform Requirements for Manuscripts Submitted to Biomedical Journals established by the International Committee of Medical Journal Editors (ICMJE) (http://www.icmje.org/).

Follow ICMJE’s General Principles and Reporting Guidelines and meet the specific requirements for the following sections: title page, abstract, introduction, methods, results, discussion, references, tables, figures, units of measurement, abbreviations, and symbols.

For consistency and style of the text, refer to the American Medical Association (AMA) Manual of Style or another internationally recognized style guideline.

These guidelines are essential to ensure the articles are presented in a clear and professional manner.

Formatting

Microsoft Word is preferred for manuscript submissions. Use a 12-point font in Times New Roman or Arial. The entire document should be double-spaced, with approximately 3 cm (1 inch) margins on all sides of the page.

Keywords

Following the abstract, include at least three keywords, separated by a comma (,). Keywords should be selected from the NLM’s MeSH (Medical Subject Headings) database: https://www.nlm.nih.gov/mesh/

Use of Artificial Intelligence (AI) Tools

The use of artificial intelligence (AI) tools such as ChatGPT, Gemini, Copilot, or Grammarly in the preparation of manuscripts is permitted only under strict ethical conditions. These tools cannot be listed as authors or co-authors, as they do not meet the authorship criteria defined by ICMJE.

Disclosure Requirement

Authors must clearly disclose the use of AI tools within the manuscript, specifying the exact role and extent (e.g., language editing, formatting, summarization). This information should be stated in the Acknowledgments or Methods section as appropriate.

Author Responsibility

All responsibility for the accuracy, originality, and ethical compliance of the content lies solely with the human authors. AI tools must not be used to generate, analyze, or interpret scientific data, nor to draw conclusions without expert oversight.

Misuse of AI Tools

The use of AI tools to fabricate data, invent citations, manipulate references, or plagiarize content constitutes a violation of academic ethics. Such misconduct will result in immediate rejection or retraction of the manuscript, and notification of relevant institutions if necessary.

Compliance with International Guidelines

This policy is aligned with the recommendations of COPE, ICMJE, WAME, and DOAJ. Authors are strongly encouraged to consult these bodies for further guidance on the ethical use of AI tools in scholarly publishing.

SCIENTIFIC ASSURANCE: ACAM

Annals of Clinical and Analytical Medicine (ACAM) upholds scientific integrity and unwavering adherence to ethical values as its core principles.

Each submission undergoes a rigorous double-blind peer-review process to ensure compliance with the highest academic standards.

This commitment reinforces both the quality of publications and the trust in scientific research, while maintaining alignment with international ethical publishing standards.

References

The number of references is limited according to the type of article: up to 25 references for research articles, 8 for case reports and surgical techniques, 85 for literature reviews, and 4 for letters to the editor.

Note: For letters to the editor, a maximum of 4 references is allowed, and the article being discussed must be cited as the first reference.

References must be formatted according to either the National Library of Medicine (NLM) (https://www.nlm.nih.gov/bsd/uniform_requirements.html) or the American Medical Association (AMA) style. If a citation generator is used, authors should carefully review the final formatting to ensure that punctuation and necessary elements are accurate and complete.

Reference Formatting Style

Our journal uses the Annals of Clinical and Analytical Medicine reference style. Authors are required to format their references accordingly. For those using EndNote reference management software, the appropriate style file can be downloaded directly.

Download EndNote Style: EndNote

Original Research Manuscripts

Original research manuscripts should be organized under the following main sections: Title Page, Abstract and Keywords, Introduction, Materials and Methods, Results, Discussion, Limitations, Conclusion, References, Tables, and Figures. Each article may include up to two tables and two figures that support the text without duplication of data. Following the Discussion, authors should include a brief Limitations paragraph summarizing the study’s constraints and a concise Conclusion emphasizing the main findings and their clinical or analytical significance. The following declarations must appear after the References section: Ethical Approval, Informed Consent, Funding, Conflict of Interest, Data Availability, Acknowledgment, Author Contributions, and Scientific Responsibility Statement.

Review Manuscripts

Review manuscripts should provide a comprehensive, balanced, and critical evaluation of the current literature on a clearly defined topic of clinical or analytical relevance. Authors are expected to demonstrate a deep understanding of the subject, identify research gaps, and synthesize evidence-based conclusions rather than merely summarizing published data. The manuscript should include the following main sections: Title Page, Abstract and Keywords, Introduction, Main Text (with relevant subheadings), Conclusion, and References. Up to three tables and three figures may be used to clarify or summarize information without repetition. The following declarations must appear after the References section: Funding, Conflict of Interest, Data Availability, Acknowledgment, Author Contributions, and Scientific Responsibility Statement. Ethical approval and informed consent are not required unless unpublished data or identifiable patient materials are used.

Case Reports Manuscripts

For ACAM submissions, authors are required to prepare case reports in line with the internationally accepted CARE Guidelines. The article title should explicitly contain the term “Case Report.” These should not exceed 1500 words, excluding the title page, abstract (limit of 150 words), and references. Each manuscript is expected to open with a structured abstract (Introduction – Case Presentation – Conclusion) and continue with the main sections: Introduction, Case Presentation, Discussion, Limitations, and Conclusion. When relevant, a timeline summarizing the clinical course should also be provided. Following the References, authors must include the mandatory Statements, covering Ethical Approval, Scientific Responsibility Statement, Animal and Human Rights Statement, and Conflict of Interest.

Case Reports and Surgical Technique Manuscripts

These should not exceed 1500 words, excluding the title page, abstract (limit of 150 words), and references. Surgical techniques should be described in detail, both in written format and visually.

Letters to the Editor

Letters to the Editor should present scientific opinions, clinical observations, questions, or critiques related to articles published in the journal within the past 12 months. The title must begin with “Comment on: [Title of the referenced article]” and include full citation details of the discussed article. The article in question should be listed as reference number 1. Submissions must not exceed 400 words and may include up to 4 references; tables or figures are accepted only in exceptional cases. Abstracts and subheadings are not required. Authors must provide their full name, institutional affiliation, and contact information. A conflict of interest statement is mandatory; if none exists, it should be clearly stated. When patient data or clinical information is included, ethical approval and written informed consent must be documented. If the work received financial support, a funding statement must be provided; if not, this should be indicated. All letters are subject to editorial review, and responses from the authors of the original article may be published when appropriate.

Editorial Comments / Discussion

Written by experts in the field and follow an article related to this area of study. Word limit: 1500 words.

Medical Education / Scientific Letter

Medical education articles focus on current medical issues and are intended to educate readers, supported by up-to-date clinical and laboratory information. Scientific letters also provide relevant information, include a related title, and references.

Images and Videos

Submitted images should be original and feature rarely seen medical cases (72 dpi resolution). Each image must include a related summary. Preferred video formats are AVI, MOV, MPG, or RM, resolution 320×240 pixels, max duration 30 seconds, 20–30 fps. Images and videos should be submitted as separate files.

Ethical Responsibilities
Absence of Animal or Human Studies

If no animal or human studies were conducted, include the following before References:
“No animal or human studies were carried out by the authors for this article.”

Animal Studies

State in the Methods section that all animals were treated ethically in accordance with the Guide for the Care and Use of Laboratory Animals. Submit a copy of the ethics approval. Include analgesia and euthanasia methods. If accurate, add:
“All institutional and national guidelines for the care and use of laboratory animals were followed.”

Human Studies

Include confirmation that informed consent was obtained. All procedures must follow institutional or national ethics standards and the 1964 Helsinki Declaration. For studies in Turkey, include compliance with the “Regulations on Pharmaceutical Research” (Official Gazette no. 27089, Dec 23, 2008). Submit ethics board approval. If a patient photo is used, written consent is required. Include the statement below if applicable:

“All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.”

Funding

All original articles, review articles, case reports, and all letter types should include a ‘Funding’ statement. A funding statement must describe who funded the study and their role. Include grant numbers and funder website URLs. If appropriate, use this statement:

“The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.”

Conflict of Interest

All original articles, review articles, case reports, and all letter types should include a ‘Conflict of Interest’ statement. Please disclose all financial resources that could be considered a potential conflict of interest regarding the manuscript or its submission.