Evaluation of erythrocyte and thrombocyte parameters in pediatric patients with diabetes mellitus

Abstract

AimTo analyze erythrocyte and thrombocyte parameters in patients with diabetes, diabetic ketoacidosis, and controls.MethodPatients who were diagnosed as having diabetic ketoacidosis (DKA) in the pediatric emergency clinic between January 2015 and January 2016 were included in group 1; patients with type 1 diabetes mellitus (DM) who consulted the pe-diatric endocrinology outpatient clinic for routine controls were included in group 2, and control patients were in group 3.ResultsA total of 108 pa-tients comprising 36 patients with DKA, 37 patients with DM, and 35 controls were involved in the study. The mean platelet volume (MPV) of the control group was significantly lower than the DKA (p= 0.001) and DM (p= 0.001) groups (p<0.01). The mean corpuscular hemoglobin concentration (MCHC) was significantly higher in the DKA group than in the DM group (p= 0.017), and the mean value of platelet distribution width (PDW) in the DKA group was found higher than that in the DM and control groups (p<0.01). There was no statistically significant difference between the groups in terms of red cell distribution width (RDW), mean corpuscular volume (MCV), and red blood cell distribution width/mean corpuscular volume (RDW/MCV) levels (p>0.05).ConclusionAn inflammatory marker, MPV, was found higher in the DKA and diabetic groups than in the normal population. High levels of MPV, RDW, PDW, and MCHC increased the risk of DKA incidence.

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