Declarations
Ethics Declarations
This study was approved by the Ethics Committee of Esenyurt University (Date: 2025-05-14, No: 2025/04-52)
Animal and Human Rights Statement
All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed Consent
Written informed consent was obtained from all participants before enrollment in the study.
Data Availability
The datasets used and/or analyzed during the current study are not publicly available due to patient privacy reasons but are available from the corresponding author on reasonable request.
Conflict of Interest
The authors declare that there is no conflict of interest.
Funding
None.
References
- De Oliveira GS Jr, Castro-Alves LJ, Nader A, Kendall MC, McCarthy RJ. Inadequate postoperative pain management is associated with persistent pain, delayed functional recovery, and longer hospital stay, which increase medical expenses and is becoming a public health issue. BMC Anesthesiol. 2019;19(1):86.
- Mishriky BM, George RB, Habib AS. Transversus abdominis plane block for analgesia after cesarean delivery: a systematic review and meta-analysis. Can J Anaesth. 2012;59(8):766-778. doi:10.1007/s12630-012-9729-1
- Zhang D, Zhou C, Wei D, Ge L, Li Q. Dexamethasone added to local anesthetics in ultrasound-guided transversus abdominis plane block for analgesia after abdominal surgery: a systematic review and meta-analysis of randomized controlled trials. PLoS One. 2019;14(1). doi:10.1371/journal.pone.0209646
- Warman P, Nicholls B. Ultrasound-guided nerve blocks: efficacy and safety. Best Pract Res Clin Anaesthesiol. 2009;23(3):313-326. doi:10.1016/j.bpa.2009.02.004
- Yan ZR, Chen LJ, Zhang SJ, et al. The transversus abdominis plane block in conjunction with intrathecal morphine use after cesarean section in women with severe preeclampsia: a randomized controlled trial. BMC Anesthesiol. 2023;23(1):100. doi:10.1186/s12871-023-02061-9
- Erol MK, Şengel A, Tammo Ö, Seçilmiş S, Kaya F. The effect of TAP block use in postoperative analgesic in cesarean section. Eur Rev Med Pharmacol Sci. 2023;27(7):2786-2793.
- Vaghela S, Chaurasiya M, Prakash R, Khan M. Ultrasound-guided quadratus lumborum block versus transversus abdominis plane block for laparoscopic inguinal hernia repair and appendicectomy using ropivacaine with dexmedetomidine. Cureus. 2023;15(1). doi:10.7759/cureus.33450
- Blanco R, Ansari T, Riad W, Shetty N. Quadratus lumborum block versus transversus abdominis plane block for postoperative pain after cesarean delivery: a randomized controlled trial. Reg Anesth Pain Med. 2016;41(6):757-762. doi:10.1097/aap.0000000000000495
- Roy A, Bhoi D, Chhabra A, Mohan VK, Darlong V, Prasad G. Quadratus lumborum block vs transversus abdominis plane block in laparoscopic transabdominal preperitoneal repair of inguinal hernia in adults: a randomised controlled trial. Indian J Anaesth. 2023;67(2):207-215. doi:10.4103/ija.ija_304_22
- Helander EM, Billeaud CB, Kline RJ, et al. Multimodal approaches to analgesia in enhanced recovery after surgery pathways. Int Anesthesiol Clin. 2017;55(4):51-69. doi:10.1097/aia.0000000000000165
- Gan TJ. Poorly controlled postoperative pain: prevalence, consequences, and prevention. J Pain Res. 2017;10:2287-2298. doi:10.2147/jpr.s144066
- Kamel BH, Ibrahim SF, Abo Seif EMK, Hassan HS. Comparison of ultrasound-guided transversus abdominis plane block versus intravenous patient-controlled analgesia for postoperative analgesia in patients undergoing lower abdominal surgeries under spinal anesthesia. QJM. 2024;117(suppl 2).025.
- Li C, Shi J, Jia H. Ultrasound-guided transversus abdominis plane block as an effective anesthetic technique for transverse colostomy in a high-risk elderly patient: a case report. Front Med (Lausanne). 2023;10:1102540. doi:10.3389/fmed.2023.1102540
- De Oliveira GS Jr, Castro-Alves LJ, Nader A, Kendall MC, McCarthy RJ. Transversus abdominis plane block to ameliorate postoperative pain outcomes after laparoscopic surgery: a meta-analysis of randomized controlled trials. Anesth Analg. 2014;118(2):454-463. doi:10.1213/ane.0000000000000066
- Alsharari AF, Abuadas FH, Alnassrallah YS, Salihu D. Transversus abdominis plane block as a strategy for effective pain management in patients with pain during laparoscopic cholecystectomy: a systematic review. J Clin Med. 2022;11(23):6896. doi:10.3390/jcm11236896
- Abdallah FW, Halpern SH, Margarido CB. Transversus abdominis plane block for postoperative analgesia after cesarean delivery performed under spinal anesthesia? A systematic review and meta-analysis. Br J Anaesth. 2012;109(5):679-687. doi:10.1093/bja/aes279
- Baaj JM, Alsatlı RA, Majaj HA, Babay ZA, Thallaj AK. Efficacy of ultrasound-guided transversus abdominis plane block for postcesarean section delivery analgesia: a double-blind, placebo-controlled, randomized study. Middle East J Anaesthesiol. 2010;20(6):821-826.
- Zhao Z, Xu K, Zhang Y, Chen G, Zhou Y. Quadratus lumborum block for postoperative analgesia after cesarean section: a meta-analysis of randomized controlled trials with trial sequential analysis. Sci Rep. 2021;11(1):18104. doi:10.1038/s41598-021-96546-7
- Haskins SC, Tseng A, Zhong H, et al. Anterior quadratus lumborum block does not provide superior pain control after hip arthroscopy: a double-blinded randomized controlled trial. Anesthesiology. 2021;135(3):433-441. doi:10.1097/aln.0000000000003853
- Verma K, Malawat A, Jethava D, Jethava DD. Comparison of transversus abdominis plane block and quadratus lumborum block for postcesarean section analgesia: a randomised clinical trial. Indian J Anaesth. 2019;63(10):820-826. doi:10.4103/ija.ija_61_19
- El Boghdadly K, Desai N, Halpern S, et al. Quadratus lumborum block vs transversus abdominis plane block for caesarean delivery: a systematic review and network meta-analysis. Anaesthesia. 2021;76(3):393-403.
- Dam M, Hansen CK, Poulsen TD, et al. Transmuscular quadratus lumborum block for percutaneous nephrolithotomy reduces opioid consumption and speeds ambulation and discharge from hospital: a single-centre randomised controlled trial. Br J Anaesth. 2019;123(2). doi:10.1016/j.bja.2019.04.054
- Yousef NK. Quadratus lumborum block versus transversus abdominis plane block in patients undergoing total abdominal hysterectomy: a randomized prospective controlled trial. Anesth Essays Res. 2018;12(3):742-747. doi:10.4103/aer.aer_108_18
- Huang L, Zheng L, Zhang J, et al. Transmuscular quadratus lumborum block versus oblique subcostal transversus abdominis plane block for analgesia in laparoscopic hysterectomy: a randomised single-blind trial. BMJ Open. 2021;11(8). doi:10.1136/bmjopen-2020-043883
- Hansen C, Dam M, Nielsen MV, et al. Transmuscular quadratus lumborum block for total laparoscopic hysterectomy: a double-blind, randomised, placebo-controlled trial. Reg Anesth Pain Med. 2021;46(1):25-30. doi:10.1136/rapm-2020-101931
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About This Article
How to Cite This Article
Melih Bestel, Elif Ucar, Abdulhakim Şengel, Nesrin Burcu Kaya, Güven Arslan, Erkan Şimşek. Comparison of the analgesic efficacy of transversus abdominis plane block and quadratus lumborum block after a cesarean section under general anaesthesia: a randomised controlled trial. Ann Clin Anal Med 2025;16(10):725-729. doi:10.4328/ACAM.22795
Publication History
- Received:
- 02.07.2025
- Accepted:
- 08.09.2025
- Published Online:
- 16.09.2025
- Printed:
- 01.10.2025


