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The relationship between depressive status and total cholesterol levels in bomb plant workers

Depression and cholesterol levels in bomb plant workers

Original Research doi:10.4328/JCAM.10.1.14 Published: January 1, 2010

Authors

Affiliations

1Department of Biochemistry and Clinical Biochemistry, Faculty of Medicine, Kırıkkale University, Kırıkkale, Türkiye.

2Department of Biochemistry and Medical NBC Defense, Gülhane School of Medicine, Ankara, Türkiye.

3Department of Internal Medicine, Faculty of Medicine, Kırıkkale University, Kırıkkale, Türkiye.

4Department of Public Health, Gülhane School of Medicine, Ankara, Türkiye.

5Department of Psychiatry, Faculty of Medicine, Kırıkkale University, Kırıkkale, Türkiye.

Corresponding Author

Levent Kenar

Abstract

AimThere is significant amount of evidence linking low cholesterol levels to aggressive behaviors, depression and suicide.
MethodsThe objective of this study was to determine whether a correlation exists between serum total cholesterol levels and depressive state in 77 male workers labouring in a bomb plant and in 80 male office personnel. Depressive statuses of the subjects were determined by using Beck Depression Rating Scale and Zung Self-Rating Depression Scale.
ResultsDepression scores were significantly higher and total cholesterol levels were significantly lower in bomb factory workers than that of office staff. In both types of workers, cholesterol levels were negatively correlated with depression scores according to both Beck and Zung scales. Total cholesterol levels of bomb factory workers with moderate and severe depression symptoms were significantly lower when compared with normal and mild depression.
ConclusionThese data indicate that low serum total cholesterol level is associated with increased risk of depressive state.

Keywords

depression cholesterol bomb plant

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About This Article

Received:
September 2, 2009
Accepted:
October 15, 2009
Published Online:
January 1, 2010
Printed:
January 1, 2010