Invitro effects of our spring water on the solubility of uric acid stones: a pilot study

Abstract

AimThe aim of this study was to evaluate the influence of our spring water on urinary analytes and stone samples in (patient with) uric acid stone.MethodsTwenty patients with uric acid stones underwent a nutritional and metabolic evaluation at baseline and after a controlled diet including our spring water. Stone samples were also left in the usual water and in the spring water. The weights of stones were measured before and 7 days after incubation.ResultsIn patients who drank spring water, there was a tendency for the mean urine pH to increase, the change was significant statistically. On the other hand, urine citrate excretion significantly also increased in these patients (P < 0.005). The differences between initial and end-dry weights of stone examples were significant statistically (P < 0.05).ConclusionThe results of our pilot study may help us to reduce uric acid stone formation and recurrence with the alkaline spring waters.

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