Factors effecting mortality on patients operated on due to gastric carcinoma

Abstract

AimThe purpose of the study is to investigate the results of data obtained from the records of patients who were operated due to gastric carcinoma in our hospital, to determine whether the evaluated variables have an effect on mortality. MethodsDemographic information (age, gender, contact information, hospital registration, and citizenship number), types of surgery performed (total/subtotal gastrectomy), histopathological diagnosis (tumor size, lymph node calculation and status), pathological stage, serum albumin levels, tumor markers, complete blood count, and survival status of 170 patients who underwent surgery due to gastric carcinoma were observed and recorded. According to these data, metastatic lymph node ratio (MLR), red cell distribution width – platelet ratio (RPR), neutrophil – lymphocyte ratio (NLR), platelet – lymphocyte ratio (PLR), and prognostic nutritional index (PNI) values were calculated. ResultsAccording to the univariate analysis of the independent variables which effect mortality, NLR, MLR, age, stage, and gender parameters were found statistically significant (P < .05). According to the multivariate analysis (Cox regression analysis), age, the stage of disease, and RPR were found statistically significant. ConclusionFor patients who underwent surgery due to gastric carcinoma, being over the age of 68, RPR rate higher than 0.038, and disease in stage 4 have been determined as prognostic factors which have negative effects on mortality.

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