Prognostic factors for 6-year survival rates of patients with COPD

Abstract

AimChronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality throughout the world. The objective of this study was to determine the factors influencing morbidity and mortality in patients hos-pitalized in a tertiary care center due to COPD exacerbation by analyzing the data of six-year follow-up.MethodThe enrolled patients were grouped as those who were alive by 2008 (n: 64) and those who were dead by 2008 (n: 114).ResultsThe groups did not differ in terms of smoking status, smoking burden (in pack-years), the presence of major comorbidities (namely coronary artery disease, congestive heart failure, hypertension and diabetes mellitus), the frequency of the patients with biomass exposure and the mean duration of exposure, the use of major drug classes prescribed for COPD, the rate of the use of LTOT, non-invasive mechanical ventilation or nebulisator, basal hemoglobin, hematocrite, white blood cell count, platelet count, erhyth-rocyte sedimentation rate, CRP levels, biochemical parameters, arterial blood gas analysis, and pulmonary function parameters other than average basal forced expiratory volume in 1 second (as percentage of predicted, which was lower in deceased group). The average lifetime with a diagnosis of COPD was 111.9±11.1 months for men and 206.5±32.2 months for women. Me-dian survival time was 96 months in men and 180 months in women with COPD.ConclusionThese results showed that FEV1 was significantly higher in people who live in, also found that women live longer than men.

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