Pulmonary Involvement in Rheumatic Diseases: HRCT Findings
İbrahim Tekeoğlu 1, Özcan Hız 1, Bülent Özbay 2, Murat Toprak 1, Serhat Avcu 3
1 Fiziksel Tıp Ve Rehabilitasyon AD, 2 Göğüs Hastalıkları AD, 3 Radyodiagnostik AD, Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Van, Türkiye
DOI: 10.4328/JCAM.276 Received: 05.05.2010 Accepted: 21.05.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):36-9
Corresponding Author: Özcan Hız, Yüzüncü Yıl Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Ana Bilim Dalı, Van, Türkiye.GSM: 05053696340 · E-mail: firstname.lastname@example.org
Aim: Systemic rheumatic disease (SRD) may affect all the components of the pulmonary system. This study was designed to investigate the frequency and pattern of pulmonary involvement of systemic collagen tissue diseases.
Material and Methods: A total of 128 patients -44 with rheumatoid arthritis (RA), 8 with giant cell arteritis, 14 with systemic lupus erythematosus (SLE), 8 with juvenile chronic arthritis, 24 with ankylosing spondylitis (AS), 6 with scleroderma, 12 with Behcet’s disease, 4 with mixed connective tissue disease (MCTD), 4 with polymyositis and 4 with dermatomyositis- who had presented to the Department of Physical Medicine and Rehabilitation/Rheumatology between January 2007 and December 2008 were included in the study. All the patients were informed about the study in detail and all gave written consent before enrollment. HRCT was performed in all patients.
Results: Pulmonary involvement was detected in 21 patients with RA (48%), in 8 patients with SLE (57%), in 16 patients with AS (67%), in 4 patients with scleroderma (67%), and in 4 patients with MCTD (50%). No pulmonary involvement was observed in patients with Behçet’s disease, polymyositis and dermatomyositis.
Conclusions: Our results suggest that patients with SRD may present with pulmonary involvement in varying degrees. Pulmonary symptoms may be underdiagnosed due to limited capacity of exercise secondary to musculoskeletal involvement. Therefore, a routine pulmonary X-ray should be performed in the process of the diagnosis and prior to treatment, even in the lack of complaints suggesting pulmonary involvement. Further investigations including HRCT should be performed if needed.
Keywords: Rheumatic Diseases, Lung Diseases, Tomography.
Clinical and Laboratory Evaluation of Anti-Microbial Efficacy of Photocatalysts
Berkant Özpolat 1, Tarık Çavuşoğlu 2, Seyhan Yılmaz 3, Ünase Büyükkoçak 4, Serdar Günaydın 3
1 Göğüs Cerrahisi AD, 2 Plastik ve Rekonstrüktif Cerrahi AD, 3 Kalp Damar Cerrahisi AD, 4 Anesteziyoloji ve Reanimasyon AD, Kırıkkale Üniversitesi Tıp Fakültesi, Kırıkkale, Türkiye
DOI: 10.4328/JCAM.262 Received: 24.04.2010 Accepted:19.05.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):32-5
Corresponding Author: Serdar Günaydın, Kırıkkale Üniversitesi Tıp Fakültesi, Kalp Damar Cerrahisi AD, Fabrikalar Mah. Kırıkkale, Türkiye. Phone: +903182252485 Faks: +903182240786 E-mail: email@example.com
Aim: This study aims at investigating and testing the tentative antimicrobial efficacy; in vitro and in- hospital applications of apatite coated ferrum titanate which is one of the new generation photocatalysts.
Material and Methods: 30 sterile petri dishes were kept under florescent light for 4 days following the application of 20 ppm apatite coated ferrum titanate aerosol. 0.5 McFarland (1.5X108 CFU/mL -CFU=colony forming unit) Pseudomonas aeruginosa and 0.5 McFarland Acinetobacter baumannii were cultured on 10 separate dishes. 10 unprocessed dishes were used as controls. Samples were evaluated for bacterial survival rate (CFUX100/CFU) after application. In the second step, same photocatalyst aerosol was applied as 0.012 L/m2 with the specific kit on the surfaces of different units within the hospital. Particle count was measured and compared before and one-month after the photocatalyst application by lumimeter.
Results: Bacterial survival rate was significantly lower on photocatalyst applied surfaces versus control for Pseudomonas aeruginosa after second day of application (p<0.001) (60±8% / 95±9%). This difference continued up to the 4th day gradually (3. day: 35±5% / 90±9%; 4. day:22±5% / 85±8%). Bacterial survival rate was significantly lower on photocatalyst applied surfaces versus control for Acinetobacter baumannii after the second day of application (55±7% / 87±8%) (p<0.01). This difference continued up to the 4th day gradually (3. day:40±5% / 80±8%; 4. day:15±5% / 78±7%). Particle count on photocatalyst applied surfaces diminished 97.15% in operating room, 95.61% in ICU, 98.30 in physicians’ room, 94.13% in wards and 97.04% in hospital kitchen.
Conclusions: As a result of our pioneering study on the evaluation of photocatalyst, we think that it may be one of the economic and safe alternative methods of hospital sterilization based on bactericidal and bacteriostatic efficacy confirmed in both laboratory and clinical applications.
Keywords: Titanium Dioxide, Anti-Infective Agents, Microbial Sensitivity Tests.
Comparison the Efficacy of Four Different Alpha Blockers in the Treatment of Benign Prostatic Hyperplasia
Doğan Atılgan, Adem Yaşar, Fikret Erdemir, Bekir Süha Parlaktaş, Nihat Uluocak, Fatih Fırat
Üroloji Anabilim Dalı, Gaziosmanpaşa Üniversitesi, Tıp Fakültesi, Tokat, Türkiye
DOI: 10.4328/JCAM.259 Received: 19.04.2010 Accepted: 04.05.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):27-31
Corresponding Author: Adem Yaşar, Gaziosmanpaşa Üniversitesi, Tıp Fakültesi, Üroloji Anabilim Dalı., 60100, Merkez, Tokat, Türkiye. Phone: +905055607039 E-mail: firstname.lastname@example.org
Aim: Benign prostatic hyperplasia (BPH) also known as nodular hyperplasia, benign enlargement of the prostate refers to the increase in size of the prostate in middle aged and elderly men. Although four different types of specific alpha blocker have been used in the treatment of BPH it remains controversial that which alpha adrenergic blocker is effective than others. The aim of this study is to compare the efficacy of 4 different alpha blockers agents on the treatment of BPH.
Material and Methods: Between June 2005 and December 2008 a total of 135 consecutive patients with diagnosed of BPH were evaluated in our clinic. Patients were randomized into four groups according to alpha blocker types as fallows: group I, doxazosin 4 mg; group II, tamsulosin 0.4 mg; group III, terazosin 5 mg; and group IV, alfuzosin 10 mg. All patients were followed up with International Prostatic Symptom Score (IPSS), maximal urinary flow rates (Qmax) and adverse effects were determined at baseline and again at least 3 months as efficacy parameters.
Results: The mean age of the patients were 59.8±5.4 years, 58.9±6.4 years, 58.7±5.1 years, and 59.2±5.5 years in group I, group II, group III, and group IV, respectively (p>0.05). After 3 months treatment with alpha blockers the improvements in IPSS were found as 2.73, 3.73, 3.55 and 4.44 in group I, group II, group III, and group IV, respectively. Maximum urine flow rates increased as 2.81 ml/sec, 3.24 ml/sec, 3.88 ml/sec and 4.49 ml/sec in group I, group II, group III, and group IV, respectively. However, among 4 alpha blockers statistically significant difference was found only between doxazosin and alfuzosin groups according to uroflowmetry and IPSS results. According to these results, when compared adverse effect, the significant difference was observed only in tamsulosine group.
Conclusions: As a result we can say that except retrograde ejaculation in tamsulosine group, adverse effects are not different between the groups. In addition, according to IPSS and uroflowmetry results the only significant difference was found between alfuzosin and doxazosin groups.
Keywords: Benign Prostatic Hyperplasia, Treatment, Alpha Blockers, Efficacy.
Asymmetric Dimethylarginine and 3-Nitrotyrosine Levels of the Heart Tissue aſter Endotoxemia
Yasemin Gülcan Kurt 1, Nurten Turkozkan 2, Halil Yaman 1, Nihal Şahin 2, Hüsamettin Erdamar 1, Gonca Ozan 2, Filiz Bircan 2, Emin Özgür Akgül 1, Tuncer Cayci 1, Mehmet Kemal Erbil 1
1 Department of Medical Biochemistry, Gülhane Military Medical Academy, 2 Department of Medical Biochemistry, Gazi University Medical Faculty, Ankara, Turkey
DOI: 10.4328/JCAM.215 Received: 01.03.2010 Accepted: 21.04.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):24-6
Corresponding Author: Yasemin Gülcan Kurt, GATA Tıbbi Biyokimya AD, 06010, Etlik, Ankara, Türkiye. Phone: +903123043323 Fax: +903123043300 E-mail: email@example.com
Aim: Oxidative and nitrosative stress are important in the pathogenesis of heart dysfunction aſter endotoxemia. Asymmetric dimethylarginine competitively inhibits nitric oxide production by displacing L-arginine. A link between asymmetric dimethylarginine and inflammation has been demonstrated recently in the prediction of cardiovascular events. Peroxynitrite is a reaction product formed by the interaction between nitric oxide and superoxide.
Material and Methods: In this study, the relationship between asymmetric dimethylarginine and L-arginine level and 3-nitrotyrosine, a stable product of peroxynitrite formation was investigated aſter endotoxemia (4 mg /kg at 6h). Measurement of asymmetric dimethylarginine and L-arginine were accomplished by high pressure liquid chromatography with fluorescent detector. 3-nitrotyrosine was quantified by high pressure liquid chromatography with electrochemical detector.
Results: Aſter administration of endotoxin asymmetric dimethylarginine and L-arginine levels did not change but 3-nitrotyrosine levels statistically significantly increased (p<0.05).
Conclusion: We could not detect any link between asymmetric dimethylarginine and peroxynitrite production in the heart tissues aſter given endotoxin using 4 mg / kg dose and at 6 h.
Keywords: Asymmetric dimethylarginine, Endotoxemia, 3-Nitrotyrosine, Heart.
Myasthenia Gravis with Thymoma: Histopathologic Examination and Rate of Complication After Surgery
Ayşe Gül Çevik, Kutsal Turhan, Alpaslan Çakan, Ali Özdil, Ufuk Çağırıcı
Göğüs Cerrahisi Anabilim Dalı, Ege Üniversitesi Tıp Fakültesi, İzmir, Türkiye
DOI: 10.4328/JCAM.205 Received: 11.02.2010 Accepted: 23.04.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):22-3
Corresponding Author: Ayşe Gül Çevik, Göğüs Cerrahi Anabilim Dalı, Ege Üniversitesi Tıp Fakültesi, Bornova, İzmir, Türkiye. GSM: +90505 3706069 E-mail: firstname.lastname@example.org
Aim: It is known that thymus and thymoma have a role in the etiopathogenesis of myasthenia gravis (MG). These associations and their effects on the survival have investigated in several studies since 17th century. The incidence of MG in patients with thymoma was reported to be 20-50% in different studies. The aim of this study is to investigate the relationship between thymoma and MG and to evaluate the rates of postoperative complications.
Material and Methods: The study included 25 patients (13 female and 12 male) and the mean age of patients was 42.3 years (range 24 to 70 years). 11 (44%) of patients had been treated with the diagnosis of MG. Eight (57%) of 14 (56%) patients without the diagnosis of MG had no symptoms and thymoma was detected accidentaly. The common symptom of the other 6 (43%) patients was cough. 9 (36%) patients were staged according to WHO classification. The other patients could not be staged according to WHO classification; because they were operated before the year of 2001. Four of patients were stage B1, 2 were stage B2, 2 were stage B3 and 1 was stage AB. Postoperative complication occured in 4 (16%) patients.
Results: MG was seen with a higher rate in cortical thymoma when compared with medullary thymoma, in immunohistochemical investigations. MG had been thought as a negative prognostic factor for thymoma but in the last years it had been reported as a positive prognostic factor due to the development of postoperative intensive care conditions, medical therapy and follow up.
Keywords: Myasthenia Gravis, Thymoma, Thymectomy, Surgery.
Measurement of TS-131, a New Monopyridinium Oxime, by High Performance Liquid Chromatography in Rat Plasma Samples
Zeki İlker Kunak 1, Emin Ozgur Akgul 2, Hakan Yaren 1, Tuncer Caycı 2, Yasemin Gulcan Kurt 2, Ibrahim Aydin 2, Halil Yaman 2, Levent Kenar 1, Tuna Subasi 3, Erdinc Cakır 2, Enis Macit 4, Ayhan Sıtkı Demir 3, Mehmet Kemal Erbil 1, Jana Zdarova Karasova 5
1 Department of Medical CBRN Defense, Gulhane Military Medical Academy, Ankara, Turkey, 2 Department of Medical Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey, 3 Department of Chemistry, Middle East Technical University, Ankara, Turkey, 4 Department of Analytical Toxicology, Gulhane Military Medical Academy, Ankara, Turkey, 5 Department of Toxicology, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
DOI: 10.4328/JCAM.238 Received: 22.03.2010 Accepted: 14.04.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):19-21
Corresponding Author: Halil Yaman, Department of Medical Biochemistry, Gulhane Military Medical Academy, 06018, Ankara, Turkey. E-mail: email@example.com
Aim: TS-131 is a monopyridinium aldoxime-type cholinesterase reactivator developed as a potential alternative to commercially available oximes. A sensitive, simple and reliable high performance liquid chromatography (HPLC) method with diode array detector was developed for the measurement of TS-131 concentrations in rat plasma samples.
Material and Methods: Male Spraque Dawley rats were treated intramuscularly with TS-131 and the samples were collected 30 min. later. Separation was carried out by HPLC using octadecyl silica stationary phase and a mobile phase consisting of 92% 0.1 M ammonium acetate and 8% methanol. Measurements were carried out at 40 0C. Quantitative absorbance was monitored at 242 nm.
Results: The calibration curve was linear through the range of 0.78–3200 μmol/L, which is well beyond the detected plasma level range of TS-131. Limit of quantitation was 0.39 μmol/L. Intra-day and inter-day precisions of the HPLC determinations gave standard deviations as 1.94 and 1.22%, respectively. After spiking, average spike recoveries ranged from 99.2% to 100.4% and, overall mean recovery of 99.8% was found.
Conclusion: A sensitive, simple and reliable HPLC method was established for the measurement of TS-131. The presented HPLC method with diyote arrray detector can also be used to determine the concentrations of several pyridinium oximes.
Keywords: TS-131, Oxime, Cholinesterase Reactivator, HPLC, Rat.
Posterior Fixation of Lumbar Burst Fractures. Comparison of Short Segment and Long Segment Pedicle Fixation
Serkan Bilgiç 1, Tolga Ege 2, Ömer Erşen 3, Kenan Koca 3, Erbil Oğuz 3, Ali Şehirlioğlu 3
1 GATF Acil Tıp Anabilim Dalı, Ankara, 2 Van Asker Hastanesi Baştabip Yardımcılığı, Van, 3 GATF Ortopedi ve Travmatoloji Anabilim Dalı, Ankara, Türkiye
DOI: 10.4328/JCAM.239 Received: 22.03.2010 Accepted: 30.03.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):15-8
Corresponding Author: Serkan Bilgiç, GATF Acil Tıp Anabilim Dalı Etlik, 06018, Ankara, Türkiye. Phone: +903123043076 Fax: +903123045500 E-mail: firstname.lastname@example.org
Aim: The aim of this study was to compare the effect of short segment and long segment posterior fixation methods on deformity correction and preservtion of correction in lumbar burst fractures.
Material and Methods: In this study we evaluate 40 patients (9 female, 31 male) treated surgically due to lumbar burst fracture between 2000 and 2008.
Results: Twenty six L2 fractures, twelve L3 fractures of 38 patients were included in this study. Sagittal deformities after the fracture were evaluated by preoperatively, postoperatively and last follow up X-rays according to anterior corpus height loss (ACHL), sagittal index and local kyphosis angle (LKA).
Conclusions: Between two groups there were no statistically difference of ACHL and LKA. In follow up there were no differrence between correction loss of two groups.
Keywords: Llumbar Burst Fracture, Posterior Instrumentation.
Comparison of two Methods for Malondialdehyde Measurement
Saad Al-Fawaeir 1, E. Özgür Akgül 1, Tuncer Çaycı 1, Hilmi Demirin 2, Yasemin Gülcan Kurt 1, İbrahim Aydın 1, Mehmet Ağıllı 1, Esin Özkan 3, Halil Yaman 1, Erdinç Çakır 1, M. Kemal Erbil 1
1 Department of Medical Biochemistry, Gülhane Military Medical Academy, Ankara, 2 Department of Medical Biochemistry, School of Medicine, Süleyman Demirel University, Isparta, 3 Department of Medical Biochemistry, School of Medicine, Fırat University, Elazığ, Turkey
DOI: 10.4328/JCAM.209 Received: 18.02.2010 Accepted: 26.03.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):11-4
Corresponding Author: Yasemin Gülcan Kurt, GATA Tıbbi Biyokimya AD 06010 Etlik, Ankara, Türkiye. Phone: +903123043323 Fax:+903123043300 E-mail: email@example.com
Aim: In this study, we aimed to measure malondialdehyde levels by two different methods and compare these methods.
Material and Methods: Serum malondialdehyde levels of 60 volunteers were measured with thiobarbituric acid test and high pressure liquid chromatography after derivatization of malondialdehyde with 2,4 dinitrophenylhydrazine and these two methods were compared.
Results: A statistically significant difference (p<0.001) has been found in serum malondialdehyde levels measured by high pressure liquid chromatography (1.85±0.09 μmol/L) and spectrophotometry (2.47±0.18 μmol/L). Cohesion between measurements made by two different methods have been evaluated and the interclass correlation coefficient has been found as 0.365 (p=0.042). Statistically significant, weak-mild degree correlation has been found between measurements (r=0.284, p=0.028).
Conclusions: High pressure liquid chromatography method for malondialdehyde measurement after derivatization with 2,4 dinitrophenylhydrazine provided a more accurate and sensitive assessment of lipid peroxidation than the conventional spectrophotometric thiobarbituric acid method.
Keywords: Malondialdehide, Lipid Peroxidation, Oxidative Stress, High Pressure Liquid Chromatography, Spectrophotometric Method.
The Effect of Diaphragmatic Plication on Pulmonary Function Test, Dyspnea Score and Arterial Blood Gases: Analysis 11 Patients with Diaphragmatic Elevation
Ufuk Çobanoğlu 1, Fuat Sayir 1, Duygu Mergan 1, Osman Toktas 2
1 Göğüs Cerrahisi Ana Bilim Dalı, 2 Genel Cerrahi Ana Bilim Dalı, Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Van, Türkiye
DOI: 10.4328/JCAM.253 Received:13.04.2010 Accepted: 05.05.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):7-10
Corresponding Author: Ufuk Çobanoğlu, Göğüs Cerrahisi Ana Bilim Dalı, Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Van, Türkiye. GSM: +905362199397 E-mail: firstname.lastname@example.org
Aim: Diaphragmatic evantration or paralysis in adults is associated with respiratory distress. In this study, we aimed to compare preoperative and postoperative pulmonary function tests, arterial blood gas analyses and dyspnea scores of the cases in whom plication had been performed for diaphragmatic elevation.
Material and Methods: Between January 2004 and March 2010 eleven adult patients who had undergone diaphragmatic plication due to diaphragmatic paralysis and eventration were analyzed. There were 7 (63.63%) men and 4 (36.37%) women aged 28-65 (mean 38 ± 2.9). Diaphragmatic plication was performed. Pulmonary function test, dyspnea scores, and arterial blood gases in the preoperative and postoperative period were studied.
Results: Dyspnea was present in all of the cases and a decrease in both FVC, FEV1, FEV1/FVC values of pulmonary function test and partial pressure of oxygen in the arterial blood were observed. In chest x-ray and thorax computed tomography, it was detected that right or left diaphragm was elevated. Diaphragmatic paralysis was detected by fluoroscopy in 6 patients. Transthoracally, diaphragmatic plication was performed to the cases. There were no postoperative complications or deaths. In postoperative six and twelve months, significant improvements in the symptoms, the values of pulmonary function tests, partial pressure of oxygen in the arterial blood and dyspnea scores of the patients were observed.
Conclusions: Diaphragmatic plication is a safe and effective procedure for adult patients with dyspnea due to unilateral diaphragmatic elevation. Lung expansion is easily achieved by performing diaphragm plication.
Keywords: Diaphragm, Eventration, Paralysis, Plication.
Retrospective Analysis of COPD Patients, Who Were Treated in Hospital (One Year Follow up)
Cantürk Taşçı, Deniz Arık, Ergün Uçar, Metin Özkan, Ergün Tozkoparan, Hayati Bilgiç
GATA Göğüs Hastalıkları AD., Ankara, Türkiye
DOI: 10.4328/JCAM.169 Received: 12.01.2010 Accepted: 19.02.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):4-6
Corresponding Author: Cantürk Taşçı, GATA Göğüs Hastalıkları AD. Etlik, Ankara, Türkiye. Phone: +905326460218 E-mail: email@example.com
Aim: The aim of this study is to evaluate the demographic and other characteristics of the patients hospitalized patients with COPD exacerbations.
Material and Methods: We evaluated the characteristics of hospitalized patients with COPD retrospectively to determine the causes of hospitalization.
Results: Eighty-one patients with COPD were hospitalized 197 times within a year. Hospitalized ones were usually hypercapnic severe COPD patients and patients with a concomitant disease had prolonged hospitalizations.
Conclusion: Severe and very severe COPD patients were hospitalized more often. Hospital stay in very severe COPD patients were longer and these patients needed non-invasive and invasive mechanical ventilatory support. Patients with concomitant disease and who were smokers hospitalized more and hospital stay was longer. Mortality was also higher in these patients.
Keywords: COPD Exacerbation, Retrospevtive Study, Mechanical Ventilation.
Physicians’ Opinions of Phytotherapy Products
Zerrin Gamsızkan 1, Alev Esen Kurt 1, Alev Yücel 2, Murat Kartal 3
1 Ankara İl Sağlık Müdürlüğü Aile Hekimliği Şubesi, 2 Ankara İl Sağlık Müdürlüğü Sağlık İl Eğitim Kurulu, 3 Farmakognozi Anabilim Dalı, Ankara Üniversitesi Eczacılık Fakültesi, Ankara, Türkiye
DOI: 10.4328/JCAM.132 Received: 07.12.2009 Accepted: 19.02.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):1-3
Corresponding Author: Zerrin Gamsızkan, Ankara İl Sağlık Müdürlüğü Aile Hekimliği Şubesi, Ankara, Türkiye. E-mail: firstname.lastname@example.org
Aim: This study has been conducted to determine of family physicians’ level of knowledge and perspectives with herbal products therapy (phytotherapy) – and herbal products.
Material and Methods: Present study, which is a type of descriptive study, is designed with the participation of the family physician specialists and assistants working public or private health organizations in several cities in between June 2007 and April 2008 by via electronic mail. In this research, a specifically developed questionnaire including 11 questions was applied for the physicians.
Results: 150 physicians participated in to the research from 30 provinces. The half of the study participants (75 people) was male. The mean age was 34.4. The 63.1% of the participating physicians stated that they applied or interested in phytotherapy. The 36.9% of physicians determined that they were against to phytotherapy or not interested. The major reasons of the opposition or indifference are lack of evidence-based and not having enough study in this subject (50.0%), the insufficient legal regulations (16.7%), only being able to be a the placebo effect (8.3%), and the thinking of being able to have harmful side effects (4.2%). There was not statistically significant difference between gender and interest in phytotherapy (p: 0.567). The 28.2% of the participating physicians stated that they ask to their patients whether using herbal products or not before their treatment or prescription.
Conclusion: Phytotherapy, which is frequently mentioned and used in currently, is a fact to be considered whether it is interested or not. Many studies show that it is useful while the physicians taking medical history to inquire about if the patient use of this any product, to detect possible interactions and harms. In addition, the studies emphasize that the production and consumption of herbal products is still not designed with legal regulation, there is no standardization of quality and evidence-based data is insufficient. It is a crucial necessity of more comprehensive studies and relevant legal regulations for health.
Keywords: Phytotherapy, Physicians.
Treatment of Iatrogenic Tracheal Laceration with Cervical Mediastinotomy and Tube Drainage; a Case Report
Berkant Özpolat 1, Cansel Atinkaya 2, Nezih Özdemir 3
1 Department of Thoracic Surgery, Kırıkkale University Faculty of Medicine, Kırıkkale, 2 Department of Thoracic Surgery, Pamukkale University Faculty of Medicine, Denizli, 3 Department of Thoracic Surgery, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
DOI: 10.4328/JCAM.240 Received: 28.03.2010 Accepted: 19.04.2010 Publihed Online: 22.04.2010
Corresponding Author: Berkant Özpolat, Kırıkkale University School of Medicine, Department of Thoracic Surgery, 71100, Kırıkkale, Turkey. GSM: 05058395247 E-mail: email@example.com
Tracheobronchial injury is a life threatening complication of endot-racheal intubation. An intubation induced tracheal laceration diag-nosed aſter massive subcutaneous emphysema, in a 7-year-old girl who underwent a cystotomy and capitonnage operation through a standard thoracotomy for pulmonary hydatid cyst is presented. She was treated with cervical mediastinotomy and tube drainage with an uneventful clinical outcome. Conservative and surgical tre-atment methods are discussed.
Keywords: Intratracheal Anesthesia, Trachea, Pneumomediastinum, Laceration, Subcutaneous Emphysema.
Treatment of an Unusual Case of Fibroepithelial Polyp (A case report)
Müjgan Güngör Hatipoğlu 1, Güliz Güncü 2, Hasan Hatipoğlu 3, Feriha Çağlayan 2
1 Oral Diagnoz ve Radyoloji, Diş Hekimliği Birimi, Sağlık Hizmetleri Eğitim Araştırma ve Uygulama Merkezi, Dumlupınar Üniversitesi, Kütahya, 2 Periodontoloji Anabilim Dalı, Diş Hekimliği Fakültesi, Hacettepe Üniversitesi, Ankara, 3 Periodontoloji, Diş Hekimliği Birimi, Dumlupınar Üniversitesi, Sağlık Hizmetleri Eğitim, Araştırma ve Uygulama Merkezi, Kütahya, Türkiye
DOI: 10.4328/JCAM.168 Received: 12.01.2010 Accepted: 21.02.2010 Printed: 01.05.2011 J Clin Anal Med 201 1;2(2):46-8
Corresponding Author: Hasan Hatipoğlu, Dumlupınar Üniversitesi, Sağlık Hizmetleri Eğitim Uygulama ve Araştırma Merkezi Hastanesi, Diş Hekimliği Birimi-Periodontoloji, Merkez Kampus, Tavşanlı Yolu 10.Km., Kütahya, Türkiye. Phone: +902742652031 E-mail: firstname.lastname@example.org
Fibroepithelial polyp has densely collagenous, well organised connective tissue and usually occurs on the hard palate beneath a maxillary denture.A 48 year old female patient with gingival overgrowth in the mandibular anterior region referred to the Department of Perio-dontology, with complaint of chewing and esthetic problems. She was using a fixed prosthesis between mandibular canine to canine. The lesion was totally excised. A second surgery, free gingival graft, was applied. Wound healing was without any problems.
Keywords: Hyperplasia, Gingiva, Oral Surgical Procedures.
Warfarin Overdose Induced Intramural Small-Bowel Hematoma (Case Report)
İbrahim Yetim, Ersan Semerci, Orhan Veli Özkan, Muhittin Temiz, Ahmet Aslan
Genel Cerrahi AD, Mustafa Kemal Üniversitesi, Tayfur Ata Sökmen Tıp Fakültesi, Hatay, Turkiye
DOI: 10.4328/JCAM.176 Received: 12.01.2010 Accepted: 06.02.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):43-5
Corresponding Author: İbrahim Yetim, Mustafa Kemal Üniversitesi Tayfur Ata Sökmen Tıp Fakültesi Genel Cerrahi A.B.D, Serinyol, Hatay, Türkiye. Phone: +903262111900, +905325060009 E-mail: email@example.com
Uncontrolled use of anticoagulants may cause bleeding. Warfa-rin-dependent spontaneous intramural hematoma of the small intestine is a rare complication. Although warfarin using pa-tients with abdominal pain were usually treated medically, sur-gical interventions should be considered in selected cases with intestinal intramural hematoma. Here we present a patient who was treated surgically to bring to mind this rare condition.
Keywords: Warfarin, Intestinal Obstruction, Hematoma.
Maxillary Mucoepidermoid Carcinoma Mimicking Odontogenic Cyst
Metin Şençimen 1, Kerim Ortakoğlu 2, Mehmet Erkan Kahraman 3, Aydın Gülses 4, Ömer Günhan 5
1 Ağız, Diş, Çene Hastalıkları ve Cerrahisi Anabilim Dalı, Diş Bilimleri Merkezi, Gülhane Askeri Tıp Akademisi, Etlik, Ankara, 2 Ağız Diş Çene Hastalıkları ve Cerrahisi Kliniği, Medicana Hastaneleri, Beylikdüzü, İstanbul, 3 KBB Servisi, Eskişehir Hava Hastanesi, Eskişehir , 4 Ağız, Diş, Çene Hastalıkları ve Cerrahisi Anabilim Dalı, Diş Bilimleri Merkezi, Gülhane Askeri Tıp Akademisi, Etlik, Ankara, 5 Patoloji Anabilim Dalı, Gülhane Askeri Tıp Akademisi, Etlik, Ankara, Türkiye
DOI: 10.4328/JCAM.170 Received: 12.01.2010 Accepted: 06.02.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):40-2
Corresponding Author: Aydın Gülses, Ağız, Diş, Çene Hastalıkları ve Cerrahisi Anabilim Dalı, Gülhane Askeri Tıp Akademisi, Diş Bilimleri Merkezi, 06018, Etlik, Ankara, Türkiye. Phone: +903123046072 Faks: +903123046020 E-mail: firstname.lastname@example.org
Mucoepidermoid carcinoma is a malignant neoplasm character-istically composed of mucus secreting cells, intermingled with neoplastic squamous cells in variable proportions. The common-est site of occurrence is the salivary glands. This paper briefly presents the surgical and prosthetic rehabilitation of a case of a maxillary mucoepidermoid carcinoma. Mucoepidermoid carcino-mas represent clinically and radiographically very similar char-actheristics with odontogenic cysts and must be differentiated from this lesions.
Keywords: Carcinoma; Mucoepidermoid; Odontogenic Cysts.
Hemangioma of The Latissimus Dorsi Muscle, a Very Rare Chest Wall Tumor
Hüseyin Melek 1, Dursun Atakul 2, Ozan Özlücan 3, Mihriban Gürbüzel 4, Elif Torun 5, Barış Medetoğlu 1
1 Göğüs Cerrahisi, 2 Plastik Cerrahi, 3 Genel Cerrahi, 4 Patoloji, 5 Göğüs Hastalıkları, Bingöl Devlet Hastanesi, Bingöl, Türkiye
DOI: 10.4328/JCAM.193 Received: 28.01.2010 Accepted: 21.02.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):49-5
Corresponding Author: Hüseyin Melek, 1. Göğüs Cerrahisi Kliniği, Yedikule Göğüs Hastalıkları ve Göğüs Cerrahisi E.A.H, Zeytinburnu, İstanbul, Türkiye. GSM: 05052581772 E-mail: email@example.com
Hemangiomas, which are among the least common benign chest wall masses, consist of dilated, tortuous, thin-walled vessels. They are typically cutaneous in location, intramuscular (IMH) location is uncommon, with a reported frequency of 0.8% among all benign vascular lesions. Hemangiomas of the latissimus dorsi muscle are very rare. Relatively rarely do they occur in young adults and are more frequent in females. A 25 year-old female patient applied to our clinic with a progressively growing painful mass lesion on her back which existed for 1 month. Physical examination revealed a firm, tender and mobile mass lesion in the inferior part of right scapula. Thoracic MRI demonstrated a well-enhanced mass lesion with 3 cm diameter. The lesion was totally excised and histopathologically diagnosed as cavernous hemangioma in latissimus dorsi muscle. Hemangiomas are extremely rare in adults and in latissimus dorsi muscle. We report this rare chest wall disorder presenting its unusual location and effective surgical treatment. The radiological, pathological and surgical images of the case are reviewed with accompanied literature.
Keyword: Hemangioma, Muscle Latissimus Dorsi, Chest Wall Tumor.
A Case of Morgagni Hernia Resulting with Respiratory Arrest
Ali Kılıçgün 1, Ahmet Oğuz Hasdemir 2, Murat Bozgeyik 2, Rıdvan Çakmaz 2 , Cavit Çöl 2
1 Göğüs Cerrahisi Anabilim Dalı, 2 Genel Cerrahi Anabilim Dalı, Abant İzzet Baysal Üniversitesi, İzzet Baysal Tıp Fakültesi, Bolu, Türkiye
DOI: 10.4328/JCAM.194 Received: 28.01.2010 Accepted: 06.02.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):52-4
Corresponding Author: Ali Kılıçgün, Karamanlı mah. Yunus Emre sok. No:1/12 Bolu, Türkiye. Phone: +903742534656 Fax:+903742534615 E-mail: firstname.lastname@example.org
Morgagni’s hernia is seen at a rate of 3-4% among all diaphragmatic hernias. It develops from a defect in the pleuroperitoneal membrane. Herniation of the omentum is seen most commonly, that of the colon frequently, and herniation of small bowel and stomach is seen rarely. When being examined due to anemia and dyspnea, a 53-year-old male patient suffered from a respiratory arrest and was hence intubated and placed under treatment at the intensive care unit. On radiological examination, a giant diaphragmatic hernia was observed bilaterally, more marked on the right side. On laparotomy, especially on the right side, the caecum, the ascending colon, the transverse colon, the appendix, the omentum and part of the small bowel was seen to be herniated. Primary diaphragmatic repair + right hemicolectomy + end-to-end ileo-transversostomy was performed. We have reported this case because it was a giant hernia which caused respiratory arrest.
Keywords: Morgagni Hernia, Emergency Surgery, Abdominal Surgery.
Sedation for Esophagogastroduodenal Endoscopy
Tayfun Aydın 1, Sacit Güleç 2
1 Anesteziyoloji ve Reanimasyon A.B.D, Dumlupınar Üniversitesi Tıp Fakültesi, Kütahya, 2 Anesteziyoloji ve Reanimasyon A.B.D, Eskişehir Osmangazi Üniversitesi Tıp Fakültesi, Eskişehir, Turkey
DOI: 10.4328/JCAM.11.2.41 Received: 31.01.2010 Accepted: 02.03.2010 Printed: 01.05.2011 J Clin Anal Med 2011;2(2):61-7
Corresponding Author: Tayfun Aydın, İstiklal Mahallesi Porsuk Bulvarı, Başkurt Apartmanı, No: 69/13, 26010, Eskişehir, Türkiye. GSM: +905332209450 Fax: +9002742652277 Email:email@example.com
Different anesthetic techniques and drugs can be used for esophagogastro-duedonal endoscopy. However, the scientists are still searching for appropri-ate drugs and protocols for sedation during esophagogastroduedonal endos-copy. The aim of this review is to discuss the topics related with sedation and esophagogastroduedonal endoscopy in the light of literature. Today standard procedure for diagnostic esophagogastroduedonal endoscopy usually con-sists of topical pharyngeal anesthesia, minimal sedation or anxiolysis, which may be complemented with analgesia when needed. When a prolonged, com-plex, or particularly troublesome or painful examination is foreseen, deeper sedation with multiple drugs and in closed observation of a staff may be required.
Keywords: Endoscopy; Gastrointestinal Endoscopy; Sedation
Tuncer Saçar 1, Handan Saçar 2
1 Özel Buca Doruk Tıp Merkezi Dermatoloji servisi, 2 Bornova Şifa Hastanesi Dermatoloji Servisi, İzmir, Türkiye
DOI: 10.4328/JCAM.116 Received: 11.12.2010 Accepted: 27.12.2010 Printed: 01.05.2011 JClinAnalMed 2011;2(2):57-60
Corresponding Author: Tuncer Saçar, Özel Buca Doruk Tıp Merkezi Dermatoloji servisi, Mehmet Akif Caddesi, İnkılap Mah. No:107, Şirinyer, İzmir, Türkiye. GSM: 05056735639 E-mail: firstname.lastname@example.org
Seborrehic dermatitis is a common inflammatory skin condition occurring most often on the face, scalp and chest. It affects between 1-3 of adults and is more common in males. It is especially common in adolescents, young adults and people older than 50 years old. Frequently, it involves scalp, naso-labial folds, ears, eyebrows and sternum. It is characterised by symetriccal erythematous papules and plaques with greasy yellow squams. The condition has multifactorial etiology and stress, atopy, Pityrosporum ovale, central ner-vous system diseases and drugs are the mostly accused factors. Antiinflam-matory, antimicotic and immunomodulatory drugs are used for therapy. In re-sistent cases, systemic steroids, isotretinoin, antimycotics and phototherapy can be tried. In this review, the literature associated with the etiology, clinical manifestations and treatment of seborrheic dermatitis is overviewed.
Keywords: Seborrheic Dermatitis, Etiopathogenesis, Pimecrolimus, Puva, Therapy.
The Bronchiectasis Case with an Atypical Presentation
Cantürk Taşçı, Yakup Arslan, Hayati Bilgiç
GATA Göğüs Hastalıkları ve Tüberküloz AD, Ankara, Türkiye
DOI: 10.4328/JCAM.157 Received: 03.01.2010 Accepted: 08.02.2010 Printed: 01.05.2011
Corresponding Author: Cantürk Taşçı, GATA Göğüs Hastalıkları ve Tüberküloz AD, Etlik, Ankara, Türkiye. Phone: +905326460218 E-mail: email@example.com
A 20 year old male patient was hospitalized with the complaints of left sided pain, cough and sputum expectoration. Postero/anterior chest x-ray showed a large opacity which occupied approximately whole part of the upper lobe of the left lung (Figure 1)…
Severe Lung Injury due to a Broken Steel Wire
Adem Güler, Mehmet Ali Şahin, Harun Tatar
GATA Kalp Damar Cerrahi Kliniği, Etlik, Ankara, Türkiye
DOI: 10.4328/JCAM.220 Received: 04.03.2010 Accepted: 01.04.2010 Printed: 01.05.2011
Corresponding Author: Adem Güler, GATA Kalp Damar Cerrahi Kliniği, Etlik, Ankara, Türkiye. Phone: +90 312 304 52 71 GSM: +90 506 531 91 11 E-mail: firstname.lastname@example.org
A 72 year old man had presented to our cardiology department with angina pectoris. After coronary angiography, coronary artery bypass surgery was performed with cardiopulmonary bypass using saphenous vein graft to the left anterior descending and the right coronary artery. On post operative 1st day his mediastinal and chest tubes removed, the patient has taken to the service and discharged on post operative 7th day without any complication. On post operative 15 th day the patient has presented to our clinic with dispnea. After first physical examination, respiratory sounds could not be oscultated at the right side of the chest. On X ray graphies; there were pneumothorax at the right side…