The Comparison of the Efficacy of Three Different Treatment Protocols on the Type 3 Chronic Prostatitis (Chronic Pelvic Pain Syndrome)
Fikret Erdemir, Fatih Fırat, Doğan Atılgan, Nihat Uluocak, Bekir Süha Parlaktaş, Adem Yaşar
Üroloji Anabilim Dalı, Gaziosmanpaşa Üniversitesi, Tıp Fakültesi, Tokat, Türkiye
DOI: 10.4328/JCAM.10.2.17 Received: 11.10.2009 Accepted: 11.12.2009 Printed: 01.05.2010J.Clin.Anal.Med. 2010;1(2):26-30
Corresponding author: Fatih Fırat, Gaziosmanpaşa Üniversitesi, Tıp Fakültesi Üroloji Anabilim Dalı, 60100, Merkez, Tokat, Türkiye. Phone: 0 5057953112, E-mail: email@example.com, firstname.lastname@example.org
Aim: In this study, the effect of three different treatment protocols on the type 3 chronic prostatitis was evaluated. In addition to our knowledge, the comparative studies which related CPPS are limited in Turkish literature.
Material and Methods: Between January 2004 and December 2008 a total of 87 male patients with diagnosed of type 3 chronic prostatitis, were evaluated in our clinic. According to treatment protocols patients with type 3 chronic prostatitis, were randomized into three groups as fallows group 1; antibiotic+anti- inflammatory+α-blocker, group 2; α-blocker and group 3; antibiotic+anti- inflammatory. Pretreatment and post treatment results were compared.
Results: The mean age of all patients was 34.14±7.68 years. The mean age of the patients was 34.13±7.39 years, 34.76±7.99 years, and 33.72±8.25 years in group 1, group 2 and group 3, respectively (p>0.05). While the improvement rates after treatment was detected 68% in group 1, these rates were found as 35.3% and 52% in group 2 and group 3, respectively. This difference was statitistically significant in combined group when compared to other groups (p=0.047).
Conclusion: Although alternative treatment researches have still been continue in type 3 chronic prostatitis which consist of 90-95% of all prostatitis. It is seen that combined treatment is beneficial. However, studies in larger, randomized and controlled series are needed to prove the effect of treatment on type 3 chronic prostatitis.
Keywords: Prostatitis, Chronic Pelvic Pain Syndrome, Treatment, Antibiotic, Αlfa-Blocker.
The Ligament of Head of Femur and Its Arteries
Yalçın Kırıcı 1, Cenk Kılıç 1, Emin Öztaş 2
1 Departments of Anatomy, 2 Histology-Embryology, Gulhane Military Medical Academy, Ankara, Turkey
DOI: 10.4328/JCAM.10.2.16 Received: 11.10.2009 Accepted: 04.01.2010 Printed: 01.05.2010 J.Clin.Anal.Med. 2010 ; 1(2): 22-25
Corresponding author: Cenk Kılıç, Gulhane Military Medical Academy Faculty of Medicine, Department of Anatomy, 06018, Ankara, Turkey. Phone: +90 312 304 35 08 Fax: +90 312 381 06 02 E-mail: email@example.com
Aim: The artery supply to head of femur and running along with the ligament of head of femur (ligamentum capitis femoris) is important for the clinician in preventing aseptic avascular necrosis disease. The purpose of this study was to investigate the course and number of the artery and the anatomic and histologic structures of the ligament.
Material and Methods: The study was conducted on 26 ligaments of head of femur taken from 13 cadavers (8 males, 5 females). Shape and length of the ligament were examined. Then, it was investigated under light microscope.
Results: The ligament was found in all cases. Although, the study was conducted on elderly cadavers, all ligaments included dense collagen fibers and several arteries. These arteries were thick. On histological evaluation, outer surfaces of all ligaments were included dense collagen fibers and synovial membrane.
Conclusion: The arteries did not run into the ligament. Furthermore, they ran into superoanterior region of the ligament. Thus, we thought that the ligament was not injured at the adduction movement and blood stream was not interrupted.
Keywords: Head of Femur, Ligamentum Capitis Femoris, Foveolar Artery.
Invitro Effects of our Spring Water on the Solubility of Uric Acid Stones: a Pilot Study
Mustafa Burak Hoşcan 1, Cem Dilmen 2, Mehmet Ekinci 1, Taylan Oksay 2, Sıtkı Orak 3, Selahattin Bedir 4, Tekin Ahmet Serel 2
1 Department of Urology, Başkent University, School of Medicine, Alanya,Antalya, 2 Department of Urology, Süleyman Demirel University, School of Medicine, Isparta, 3 Burdur Medical High School, Isparta, 4 Department of Urology, Gülhane Military Medical Academy, Ankara, Turkey
DOI: 10.4328/JCAM.10.2.14 Received: 23.09.2009 Accepted: 18.11.2009 Printed: 01.05.2010J.Clin.Anal.Med. 2010;1(2): 15-17
Corresponding author: Mustafa Burak Hoşcan, Başkent University Alanya Research and Practice Hospital 07400 Alanya, Antalya, Turkey. GSM: +905324364855 Fax: +90 242 5112350 E-mail: firstname.lastname@example.org
Aim: The aim of this study was to evaluate the influence of our spring water on urinary analytes and stone samples in (patient with) uric acid stone.
Material and Methods: Twenty patients with uric acid stones underwent a nutritional and metabolic evaluation at baseline and after a controlled diet including our spring water. Stone samples were also left in the usual water and in the spring water. The weights of stones were measured before and 7 days after incubation.
Results: In patients who drank spring water, there was a tendency for the mean urine pH to increase, the change was significant statistically. On the other hand, urine citrate excretion significantly also increased in these patients (p<0.005). The differences between initial and end-dry weights of stone examples were significant statistically (p<0.05).
Conclusion: The results of our pilot study may help us to reduce uric acid stone formation and recurrence with the alkaline spring waters.
Keywords: Uric Acid Stone, Solubility of Stones, Spring Water.
Comparative Evaluation of Microleakage for Different Root Canal Sealers and Irrigation Solutions
Tülin Ertan 1, Yaşar Meriç Tunca 2
1 Department of Endodontics, Turkish Naval Headquarters Infirmary, 2 Department of Endodontics, Gulhane Military Medical Academy Dental Science Center, Ankara, Turkey
DOI: 10.4328/JCAM.10.2.13 Received: 08.09.2009 Accepted: 22.11.2009 Printed: 01.05.2010J.Clin.Anal.Med. 2010;1(2): 9-14
Corresponding author: Tülin Ertan, Department of Endodontics, Turkish Naval Headquarters Infirmary, Ankara, Turkey. Phone: +090 312 4032411 E-mail: email@example.com
Aim: The aim of the study was to examine the sealing ability of a root-canal sealer using different endodontic irrigants and to measure the microleakage using a fluid transport model.
Material and Methods: 170 maxillary and mandibular anterior human teeth with single bilnded were selected for this study. The root canals were instrumented using the crown-down technique with HERO- Shaper and were irrigated with 5.25 % NaOCl. The smear layer was removed by washing in 10 ml of 17% EDTA. The specimens randomly divided into 16 groups (root-canal sealings; Sealite- Ultra, Diaket, AH-Plus, Ketac-Endo and irrigation solutions; NaOCl, 2 % CHX, 1% CHX gel+NaOCl, 1% CHX gel+SS ) of ten teeth and two control groups of five teeth and obturated by lateral condensation. In order to measure the microleakage, a fluid transport model was used and leakage value for each group was calculated and recorded. Four specimens from each group were used for SEM examinations (scanning electron microscopy).
Results: The best results are taken when Ketac-Endo with 2% CHX solution used. The results proved that there is no significant difference between root-canal sealers. As for irrigant solutions, NaOCl solution caused more microleakage than 1% CHX Gel+SS and 1% CHX Gel+NaOCl solutions and the results are statistically significant.
Conclusion: The study shows that the best irrigant solutions for all root- canal sealers are 1% CHX+SS and 1% CHX+NaOCl.
Keywords: Microleakage, Fluid Transport Model, Irrigation Solutions, Root Canal Sealer, Scanning Electron Microscopy, CHX Gel.
Anaerobic Glycolysis is the Main Pathway for Energy Generation in Hl-60 Acute Promyelocytic Leukemia Cells
Hakan Boyunaga 1, Hatice Keles 2, Levent Kenar 3, Ali Ugur Ural 4, Ferit Avcu 4
1 Department of Biochemistry and Clinical Biochemistry, Kırıkkale University Faculty of Medicine, Kırıkkale, 2 Departments of Internal Medicine, Kırıkkale University Faculty of Medicine, Kırıkkale, 3 Department of Biochemistry and Medical NBC Defense, Gulhane School of Medicine, Ankara, 4 Department of Hematology, Gulhane School of Medicine, Ankara, Turkey
DOI: 10.4328/JCAM.10.2.12 Received: 02.09.2009 Accepted: 15.10.2009 Printed: 01.05.2010J.Clin.Anal.Med. 2010;1(2): 5-8
Corresponding author: Hakan Boyunaga. Department of Biochemistry and Clinical Biochemistry, Kırıkkale University Faculty of Medicine, Kırıkkale, Turkey. Phone: +90 312 304 33 29, E-mail: firstname.lastname@example.org
Aim: In physiological conditions, normal cells use mainly the glycolytic aerobic pathway to provide energy. However, most cancer cells utilize anaerobic glycolytic way for energy generation. Aim of this study was to investigate the carbohydrate metabolic pathways of HL-60 acute promyelocytic leukemia cells for energy production.
Material and Methods: Leukemia cells as well as normal leukocytes were incubated with radiolabelled glucose in aerobic and anaerobic conditions and glycogen consumptions and the ratios of radiolabelled glucose catabolized into CO2 or lactate, that is, the rates of aerobic or anaerobic glycolysis, were determined.
Results: The glycogen consumption was significantly higher in aerobic leukemia cell culture than normal leukocyte culture (p<0.01). The rate of anaerobic glycolysis was 93.8% in leukemia cells in aerobic conditions and it increased to 96.6% while utilization of glycogen increased by 7.31% in anaerobic conditions.
Conclusion: In conclusion, principally anaerobic glycolysis is effective for energy generation in HL-60 promyelocytic leukemia cells. This result may be important for the development of new therapeutic approaches in the treatment of promyelocytic leukemia, requiring further comprehensive studies.
Keywords: Energy Metabolism, HL-60 Promyelocytic Leukemia Cell, Glycogen Degradation.
The Impact of Co-Existing Prostate Adenocarcinoma with Bladder Carcinoma on Disease Specific Survival of the Patients in Our Radical Cystoprostatectomy Series
Özgür Uğurlu, Volkan Öztekin, Murat Koşan, Ömer Gökhan Doluoğlu, Öztuğ Adsan, Mesut Çetinkaya
2. Üroloji Kliniği, Ankara Numune Eğitim ve Araştırma Hastanesi, Ankara, Türkiye
DOI: 10.4328/JCAM.10.2.11 Received: 27.08.2009 Accepted: 12.11.2009 Printed: 01.05.2010J.Clin.Anal.Med. 2010;1(2):1-4
Corresponding author: Ömer Gökhan Doluoğlu, Ankara Numune Eğitim ve Araştırma Hastanesi 2. Üroloji Kliniği, Ceyhun Atıf Kansu Cd. Cevizlidere Mah. 158/11, Balgat, Ankara, Türkiye. Phone: +90312 508 52 85 E-mail: email@example.com
Aim: The aim of this study was to compare the patients with and without histologically proven prostate carcinoma who underwent radical cystectomy for muscle invasive bladder cancer in terms of bladder tumor properties and survival rates.
Material and Methods: A total of 149 male patients who had undergone radical cystectomy and urinary diversion between 1994-2007 in our institution were included in our study. Medical records of the patients were analyzed retrospectively. Fourteen (9.3%) patients had co-existing prostate carcinoma, while remaining 135 (90.7%) did not. The two groups were compared to each other with respect to the oncological properties of the bladder tumors (stage and grade) and disease specifific mortality rates.
Results: The mean ages for the patients with and without co-existing prostate carcinoma were 64.2±8.4 and 57.7±10.8, respectively. There was a signifificant difffference between the ages of the two groups (p=0.029). There were not any signifificant difffferences among the two groups regarding bladder cancer pathological stage (p=0.199) and grade (p=0.544). The disease specifific survival rates of the two groups for three years were: 61.76% and 81.82% for the patients with and without coexisting prostate carcinoma respectively. No signifificant difffference was observed between the disease specifific survival rates of the two groups (p=0.325).
Conclusion: The co-existing prostate carcinoma had no signifificant effffect on tumor stage, grade and disease specifific survival rates of patients who underwent radical cystectomy for muscle invasive bladder cancer.
Keywords: Prostate Adenocarcinoma, Cystoprostatectomy, Survival.
A Leser-Trelat Syndrome Associated with Renal Adenocarsinoma and Benign Prostat Hypertrophia
Tuncer Saçar 1, Handan Saçar 2
1 Dermatoloji servisi, Özel BucaDoruk Tıp Merkezi, 2 Dermatoloji Servisi, Bornova Şifa Hastanesi, İzmir, Türkiye
DOI: 10.4328/JCAM.10.2.25 Received: 12.11.2009 Accepted: 02.01.2010 Printed: 01.05.2010 J.Clin.Anal.Med. 2010 ; 1(2): 44-46
Corresponding author: Tuncer Saçar, Mehmet Akif Caddesi, İnkılap Mah. No:107, Şirinyer, İzmir, Türkiye. Phone: +90 232 487 60 60 E-mail: firstname.lastname@example.org
Lesser-Trelat is generally known to be one of the cutaneous findings of vicceral occult cancer and is associated with diffuse seboreic ceratosis. That finding is an important clue for a clini-cian and when is noticed it has to be cleared up whether there is a vicceral occult cancer. We report a case with leser-trelat syn-drome, thought to be associated both with renal adenocarsino-ma and benign prostat hypertrophia present in a same patient.
Keywords: Leser-Trelat, Occult Cancer, Renal Adenocarcinoma, Benign Prostat Hypertrophy.
Primary “Lymphoepithelioma-Like Carcinoma” of the Lung
Ülkü Yazıcı, Erkmen Gülhan, Ertan Aydın, Pınar Yaran, İrfan Taştepe
Göğüs Cerrahisi Kliniği, Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Ankara, Türkiye
DOI: 10.4328/JCAM.10.2.24 Received: 10.11.2009 Accepted: 05.12.2009 Printed: 01.05.2010 J.Clin.Anal.Med. 2010 ; 1(2): 40-43
Corresponding author: Ülkü Yazıcı, Department of Thoracic Surgery, Atatürk Training and Research Hospital for Chest Disease and Chest Surgery, Sanatoryum Caddesi Keçiören, Ankara 06280 Turkey. Phone: +90312 355 21 10 Fax :+9 0312 355 21 35 E-mail: email@example.com
Primary Lymphoepithelioma-like Carcinoma of the lung is commonly encountered in the nasopharyngeal region. The oral cavity, salivary glands, lung and stomach are other sites of localization. Primary Lymphoepithelioma-like Carcinoma of the lung is very rare. In our clinic 3 male and 1 female patients have been diagnosed as Lymphoepithelioma-like Carcinoma between 2000-2007. Mean age was 33. 25 years (range from 22 to 49). 2 patients presented as left hilar, 1 as right hilar, and 1 as tracheal mass. One patient was given radiotherapy after a left pneumonectomy. The remaining 3 patients received chemotherapy: 1 due to esophageal invasion, and the other 2 after biopsy via thoracotomy. All patients are still under follow-up.Lymphoepithelioma-like Carcinoma is common in the Asian population. Publications including long-term follow-up such patients are limited and the issue needs more research. Current articles state that the optimal median survival is 2 years.
Keywords: Lymphoepithelioma-Like Carcinoma, Lung, Epstein-Barr Virus, Surgery.
Tracheobronchopathia Osteochondroplastica: Owing to a Case
Burçin Çelik 1, Salih Bilgin 2
1 Göğüs Cerrahisi Anabilim Dalı, Ondokuz Mayıs Mayıs Üniversitesi Tıp Fakültesi, 2 Göğüs Hastalıkları Kliniği, Samsun Göğüs Hastalıkları ve Göğüs Cerrahisi Hastanesi, Samsun, Türkiye
DOI: 10.4328/JCAM.10.2.23 Received: 07.11.2009 Accepted: 22.12.2009 Printed: 01.05.2010 J.Clin.Anal.Med. 2010 ; 1(2):37-39
Corresponding author: Burçin Çelik, 19 Mayıs Üniversitesi Tıp Fakültesi Göğüs Cerrahisi AD, Kurupelit, 55139, Samsun, Türkiye. Phone: +90 362 312 19 19/2701 Fax: +90 362 457 60 41 E-mail: firstname.lastname@example.org
Tracheobronchopathia osteochondroplastica (TBO) is a rare be-nign disease characterized by the presence of the submucosal nodules projecting into the tracheobronchial tree. This disease is usually asymptomatic and has a benign course. A 61-year old man was admitted with cough and hemoptysis for further evalu-ation. A chest computed tomography demonstrated emphysema and subpleural bullea in both upper lobes, and consalidation in the left lower lobe. A fiberoptic bronchoscopy revealed multiple white, irregular nodules on the anterior and lateral walls of the trachea extending to the level of the carina. The patient was dis-charged with medical therapy. TBO should be considered in the differential diagnosis as an unusual cause of persistent cough, hemoptysis, persistent atelectasis and recurrent segmental or lobar infection. There is no specific therapy for this entity. The prognosis of TBO is generally good and depends on the extent and the location of the lesions.
Keywords: Tracheobronchopathia Osteochondroplastica, Bronchoscopy, Diagnosis.
Bifid Rib ; Report of Two Cases and the Efficacy of 3-Dimensional Computed Tomography
Hasan Volkan Kara¹, Kadir Ağladıoğlu¹, Mehmet Deniz Bulut² ,Ufuk Çobanoğlu³, Serhat Oğuz¹
¹Göğüs Cerrahisi Kliniği, Van Asker Hastanesi, ²Radyoloji Kliniği, Yüzüncü Yıl Üniversitesi Tıp Fakültesi, ³Göğüs Cerrahisi Kliniği, Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Van, Türkiye
DOI: 10.4328/JCAM.10.2.21 Received: 27.02.2009 Accepted: 16.10.2009 Printed: 01.05.2010 J.Clin.Anal.Med. 2010 ; 1(2): 31-33
Corresponding author: Hasan Volkan Kara, Göğüs Cerrahisi Uzmanı, Van Asker Hastanesi, Van, Türkiye. GSM: 0 532 409 74 44 • 0 505 237 90 10, E-mail: email@example.com.
Congenital anomalies of ribs exist between 0.15% to 30%. These patients have minor symptoms or totally symptom-free. They are generally diagnosed accidentally. There are case report of bifid (forked) ribs in the literature. Bifid rib should be differ-enciated from other pathological situation of lung and chest wall including malignancies. 3-dimensional(3-D) computed to-mography (CT) is a very effective diagnostic tool in differencial diagnosis of bifid rib . We present 2 cases of bifid rib that had the diagnosis by f 3 dimentional (3-D)computed tomography (CT) with the demonstrative images .
Keywords: Bifid Rib; Forked Rib; 3D CT.
Multiple Intestinal Perforation Due to Wegener’s Granulotamosis: Case Report
Nazif Zeybek 1, Özcan Altınel 1, Faik Yaylak 1,Özgür Albuz 1, Ayper Kaya 2
1 Genel Cerrahi Anabilim Dalı, 2 Patoloji Anabilim Dalı, Gülhane Askeri Tıp Akademisi, Askeri Tıp Fakültesi, Etlik, Ankara, Türkiye
DOI: 10.4328/JCAM.10.2.22 Received: 30.09.2009 Accepted: 12.11.2009 Printed: 01.05.2010 J.Clin.Anal.Med. 2010 ; 1(2): 34-36
Corresponding author: Faik Yaylak, Gülhane Askesi Tıp Akademisi, Askeri Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Etlik, Ankara, Türkiye. GSM: +90 533 338 68 99, E-mail: firstname.lastname@example.org
Wegener’s granulomatosis is one of the well known vasculitis, which results with necrotizing granulomatous lesions in the upper and lower respiratuary system and glomerulonephritis. Vasculitis is also observed in several other tissues and organ systems including gastrointestinal system. However, gastrointestinal involvement in Wegener’s granulomatosis is extremely rare. This report presents a patient with Wegener’s granulomatosis, who was diagnosed to have multiple intestinal perforations.
Keywords: Wegener’s Granulomatosis, Vasculitis, Acute Abdomen, Intestinal Perforation.
Management of Parapneumonic Effusions
Richard W. Light
Professor of MedicineVanderbilt University, Nashville, Tennessee, USA
DOI: 10.4328/JCAM.10.2.41 Received: 17.01.2010 Accepted: 30.01.2010 Printed: 01.05.2010 J.Clin.Anal.Med. 2010;1(2).47-50
Corresponding Author: Richard W. Light, Professor of Medicine, Vanderbilt University, Nashville, Tennessee, USA. E-mail: email@example.com
Pleural effusions associated with pneumonia (parapneu-monic effusions) are one of the most common causes of exudative pleural effusions in the world . Approximately 20 to 40% of patients hospitalized with pneumonia will have an accompanying pleural effusion . The presence of a pleural effusion is associated with worse outcomes in patients with pneumonia. In one study of patients hospitalized with pneumonia the mortality risk was 6.5 times higher if the patient had bilateral pleural effusion and 3.7 times higher if the effusion was unilateral than if the patient had no pleural effusion . At least part of the increased mortality with parapneumonic effusions is due to mismanagement of the pleural effusion.The likelihood of developing a pleural effusion with a bacterial pneumonia is dependent upon the organism re-sponsible for the pneumonia. The distribution of organisms responsible for parapneumonic effusions is quite different from the distribution of organisms responsible for pneumonia in general. Organisms responsible for community and hospital acquired pneumonia with complicated parapneumonic effusions also differed consider-ably in a recent multicenter study from the United King-dom . For the 336 patients with community acquired pneumonias with parapneumonic effusions in whom the responsible bacteria were identified, the most common organisms were Strept. Milleri group 32%, anaerobes 16%, Strep. pneumoniae 13% and Staph. aueus 11%. For the 60 patients with hospital-acquired pneumonia, the most common organisms were multiple resistant Staph. aureus 28%, other Staph. 18%, Enterobacteriacea 15% and Enterococci 13% . These numbers should be kept in mind when selecting antibiotics for patients with parapneumonic effusions.
Giant Dissecting Aortic Aneurysm Imitating Pleural Effusion
Göktürk Fındık, Seray Kalaycıoğlu Hazer, Sadi Kaya
Department of Thoracic Surgery, Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Ankara, Turkey
DOI: 10.4328/JCAM.10.2.31 Received: 26.11.2009 Accepted: 17.12.2009 Printed: 01.05.2010
Corresponding author: Göktürk Fındık, Department of Thoracic Surgery, Atatürk Chest Diseases and Chest Surgery Education and Research Hospital, Ankara, Turkey. Phone: +90 312 355 21 10 Email: firstname.lastname@example.org
62 years old male patient, was admitted to our clinic suffering severe dyspnea. Breath sounds are absent on the left side. The chest graphy, pleural effusion was seen on the left hemythorax (Figure 1). Thoracoabdominal computed tomography showed giant aortic ane-urysm that filled half of the left hemythorax and bilateral polycystic kidney (Figure 2-3).